{"id":"W248620978","doi":"10.1016/j.jim.2015.05.002","title":"Methods to monitor monocytes-mediated amyloid-beta uptake and phagocytosis in the context of adjuvanted immunotherapies","year":2015,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"GlaxoSmithKline Biologicals; Natural Sciences and Engineering Research Council of Canada; GlaxoSmithKline","keywords":"Phagocytosis; Context (archaeology); Internalization; Antibody; Amyloid (mycology); Monoclonal antibody; Immunology; Chemistry; Biology; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005007388,0.0002353589,0.0009681971,0.0003440406,0.00005037698,0.00003237919,0.0003355102,0.0001597173,0.00004629182],"category_scores_gemma":[0.003107743,0.0001217344,0.0002365943,0.0005797181,0.0002813019,0.0001371705,0.0001017046,0.000572351,0.000006311294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001180241,"about_ca_system_score_gemma":0.0001893595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000696747,"about_ca_topic_score_gemma":0.000001133712,"domain_scores_codex":[0.9953986,0.002702782,0.0008774564,0.0001933362,0.0004700614,0.0003577636],"domain_scores_gemma":[0.9962789,0.002178469,0.0003807941,0.0003303034,0.0005135746,0.0003179523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01120933,0.001628382,0.009409996,0.00003683939,0.00753307,0.0003595639,0.003131167,0.000002586031,0.09961481,0.0001233207,0.00015017,0.8668008],"study_design_scores_gemma":[0.02551814,0.01967515,0.6964866,0.0006749802,0.001604079,0.0009947981,0.03277688,0.0001847907,0.2126007,0.001936784,0.007019334,0.0005277054],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8628938,0.1304073,0.003673301,0.002092008,0.0001596352,0.0005522505,0.0000133625,0.00001433274,0.0001940066],"genre_scores_gemma":[0.6935154,0.00200991,0.3040428,0.0003273407,0.00005315752,0.00002270314,0.000002598749,0.00001589692,0.00001019707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.866273,"threshold_uncertainty_score":0.4964185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1205323458973086,"score_gpt":0.4481242386350672,"score_spread":0.3275918927377586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}