{"id":"W2487889560","doi":"10.1016/j.str.2016.07.005","title":"The Proteasome: More Than a Means to an End","year":2016,"lang":"en","type":"letter","venue":"Structure","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Ubiquitin; Proteasome; Scopus; Receptor; Chen; Computational biology; Chemistry; Protein degradation; Cell biology; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003076586,0.0009144171,0.001484097,0.0005185664,0.002179819,0.004277571,0.001534966,0.02871493,0.003917675],"category_scores_gemma":[0.009175313,0.0005272683,0.0007205259,0.0004478266,0.006418535,0.006529827,0.00227812,0.03237633,0.003566369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002970216,"about_ca_system_score_gemma":0.001396708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005302014,"about_ca_topic_score_gemma":0.001052804,"domain_scores_codex":[0.9982045,0.0005273963,0.0001599263,0.0002561845,0.0006508066,0.0002012613],"domain_scores_gemma":[0.9961854,0.002093423,0.0003479031,0.0003230405,0.0003531807,0.0006970047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003812638,0.00008206991,0.0004108323,0.0001833572,0.00003677205,0.004758643,0.0001537655,0.0001505776,0.00131152,0.03518895,0.9123765,0.04496573],"study_design_scores_gemma":[0.0001911502,0.00009663388,0.0004160659,0.0001459724,0.00002455151,0.004609235,0.0001604262,0.0004841884,0.0008867201,0.09669552,0.8962482,0.00004135556],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.0005498708,0.01400386,0.0004844358,0.9533151,0.02865417,0.00000587627,0.00001352171,0.00003367407,0.002939489],"genre_scores_gemma":[0.01782716,0.01776153,0.001265605,0.7535482,0.1946884,0.00003858258,0.000032273,0.00003672388,0.01480149],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.02871493,"threshold_uncertainty_score":0.02155054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00894826908464083,"score_gpt":0.2472387981774705,"score_spread":0.2382905290928297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}