{"id":"W2487889560","doi":"10.1016/j.str.2016.07.005","title":"The Proteasome: More Than a Means to an End","year":2016,"lang":"en","type":"letter","venue":"Structure","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Ubiquitin; Proteasome; Scopus; Receptor; Chen; Computational biology; Chemistry; Protein degradation; Cell biology; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001212027,0.000423956,0.0002262907,0.0000413897,0.0002647212,0.0001055029,0.0008764706,0.001075699,0.0001511947],"category_scores_gemma":[0.00008041385,0.000239879,0.0001503664,0.00006919679,0.0001527325,0.000003167897,0.0002131696,0.0007448229,0.00002983611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002283051,"about_ca_system_score_gemma":0.0001567877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001335613,"about_ca_topic_score_gemma":0.00007999331,"domain_scores_codex":[0.9980148,0.0001508572,0.0002009532,0.0006909911,0.0003283378,0.0006140771],"domain_scores_gemma":[0.9984097,0.00001651301,0.0001205356,0.001208897,0.0001098897,0.0001344378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006086252,0.000002745332,0.0000425904,0.00004870905,0.00009159273,0.00003200498,0.0001412073,0.000001000416,0.1525957,0.00004442548,0.8339394,0.01299974],"study_design_scores_gemma":[0.000157957,0.0002151737,0.00008043818,0.00003473357,0.00001774325,0.00004695996,0.00002036198,5.112003e-7,0.1073434,0.0008202508,0.8908958,0.0003666845],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.05154146,0.001282351,0.0003042199,0.9333804,0.001760003,0.003058525,0.004090951,0.0001011814,0.004480915],"genre_scores_gemma":[0.07668906,0.0001225839,0.001134543,0.8399837,0.0459335,0.0005331763,0.003143924,0.0003473016,0.03211224],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.09339672,"threshold_uncertainty_score":0.9781981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00894826908464083,"score_gpt":0.2472387981774705,"score_spread":0.2382905290928297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}