{"id":"W2489140367","doi":"10.1101/gad.284091.116","title":"Metabolites: messengers between the microbiota and the immune system","year":2016,"lang":"en","type":"review","venue":"Genes & Development","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":445,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European Research Council; Israel Science Foundation; Boehringer Ingelheim Fonds; Kenneth Rainin Foundation; Centre National de la Recherche Scientifique; Canadian Institute for Advanced Research; Rising Tide Foundation; Minerva Foundation; Benoziyo Endowment Fund for the Advancement of Science; Leona M. and Harry B. Helmsley Charitable Trust","keywords":"Biology; Immune system; Host (biology); Microbial metabolism; Innate immune system; Microbiome; Computational biology; Gut flora; Orchestration; Cell biology; Bacteria; Immunology; Ecology; Bioinformatics; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003028385,0.0008569563,0.001078809,0.00164162,0.0004283448,0.001491051,0.0007373762,0.001339389,0.004064382],"category_scores_gemma":[0.0003734225,0.0002475305,0.0003491371,0.00179173,0.0006435721,0.001384856,0.0009797012,0.001730901,0.003247826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006528856,"about_ca_system_score_gemma":0.0009769514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004773056,"about_ca_topic_score_gemma":0.0008261029,"domain_scores_codex":[0.9998585,0.00002603378,0.00001581658,0.00002671477,0.00005275394,0.000020064],"domain_scores_gemma":[0.9998686,0.00004913414,0.00002155647,0.00000584939,0.00003117424,0.00002360568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000970559,0.0000722195,0.0002628858,0.01157488,0.0000862291,0.0005204304,0.0001532688,0.0003458904,0.01690028,0.01738839,0.02640223,0.9261963],"study_design_scores_gemma":[0.000006728087,0.00003923211,0.0004333796,0.00112332,0.00003405152,0.0008542998,0.00006253574,0.0000446904,0.002075868,0.00323088,0.9920799,0.00001523796],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003248473,0.9956755,0.0004778744,0.0004697065,0.0004087298,0.000006239914,0.00004017723,0.00002425872,0.00257254],"genre_scores_gemma":[0.002238018,0.9945205,0.0005450654,0.0002580729,0.0002645998,0.00001092025,0.00004727534,0.000004079485,0.002111577],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004064382,"threshold_uncertainty_score":0.01359671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01861190731864826,"score_gpt":0.2792162758568162,"score_spread":0.260604368538168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}