{"id":"W2489425084","doi":"10.1016/j.eururo.2016.07.032","title":"Enzalutamide in Men with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer: Extended Analysis of the Phase 3 PREVAIL Study","year":2016,"lang":"en","type":"article","venue":"European Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":419,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"National Cancer Institute","keywords":"Medicine; Enzalutamide; Prostate cancer; Oncology; Chemotherapy; Internal medicine; Docetaxel; Urology; Gynecology; Cancer; Androgen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004982217,0.0001543194,0.0004039917,0.0002481921,0.00004579061,0.000007695868,0.0001507363,0.00001461469,0.0002243002],"category_scores_gemma":[0.00004446116,0.00006808287,0.00007979196,0.000757512,0.0002110637,0.00004638744,0.00004231967,0.0001144049,0.00000695691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009170779,"about_ca_system_score_gemma":0.0001856795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001638458,"about_ca_topic_score_gemma":0.000669256,"domain_scores_codex":[0.998184,0.0005937396,0.0003362625,0.0003344332,0.0002714684,0.0002800467],"domain_scores_gemma":[0.9991238,0.0001062863,0.0001569533,0.000433597,0.000107437,0.00007200224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02936999,0.006239229,0.6577779,0.0001144699,0.01184062,0.001634842,0.01389977,0.0002479239,0.2118217,0.00007549798,0.0005563786,0.06642164],"study_design_scores_gemma":[0.02323962,0.004483933,0.9631703,0.00004419815,0.002259031,0.00001028632,0.0005855229,0.0001587748,0.005024325,0.00001776003,0.0008763907,0.0001298352],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931764,0.0004714508,0.00001711844,0.002891812,0.00001959368,0.001207122,0.00005998406,0.00001717683,0.002139338],"genre_scores_gemma":[0.9965562,0.0002056327,0.00003310241,0.000157808,0.00001949606,0.00007196477,0.000008721425,0.00002774456,0.002919385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3053924,"threshold_uncertainty_score":0.2776339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02552419789789771,"score_gpt":0.3359378952628794,"score_spread":0.3104136973649816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}