{"id":"W2489482795","doi":"10.18143/jisanh_v3i2_1010","title":"iRAGE AS A NOVEL CARBOXYMETHYLATED PEPTIDE THAT PREVENTS AGE-INDUCED APOPTOSIS AND ENDOPLASMIC RETICULUM STRESS IN VASCULAR SMOOTH MUSCLE CELLS","year":2016,"lang":"en","type":"article","venue":"","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Rage (emotion); Glycation; Endoplasmic reticulum; Cell biology; Apoptosis; Receptor; Signal transduction; Inflammation; Chemistry; Unfolded protein response; Biology; Endocrinology; Internal medicine; Biochemistry; Immunology; Medicine; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002502288,0.0002041851,0.0001832328,0.0001006937,0.00004960645,0.00002487185,0.0002226728,0.0001651336,0.00007601004],"category_scores_gemma":[0.0001797229,0.0001544713,0.0000594667,0.0001608598,0.00008383178,0.00001442626,0.0002164598,0.0001192845,0.00001759492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003002724,"about_ca_system_score_gemma":0.00006838464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001962251,"about_ca_topic_score_gemma":0.00008267521,"domain_scores_codex":[0.9983605,0.0001141771,0.0002140623,0.0006579586,0.0002502987,0.0004030331],"domain_scores_gemma":[0.9991193,0.00003878138,0.00006792514,0.0005636818,0.00007238498,0.0001379652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003000465,0.00009432805,0.0005246127,0.00002516175,0.00003174294,0.000004283899,0.00005784501,0.00002796659,0.9950001,0.0000221521,0.00005062851,0.004131238],"study_design_scores_gemma":[0.001322914,0.0001446168,0.003662116,0.00004614967,0.000009290546,0.000001373538,0.00009588402,0.00001822158,0.9903569,0.00007341617,0.004032277,0.0002368931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965932,0.0001784273,0.00109189,0.0002060355,0.00007742789,0.0004339076,0.00002479548,0.00001997725,0.00137434],"genre_scores_gemma":[0.9949436,0.0007071407,0.001214428,0.0000780712,0.00005251892,0.00005010808,0.00003396393,0.0000366506,0.002883589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004643189,"threshold_uncertainty_score":0.6299158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01772004285106069,"score_gpt":0.2720824782626279,"score_spread":0.2543624354115672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}