{"id":"W2489746138","doi":"10.1182/blood.v126.23.2944.2944","title":"Comparing Single-Agent Ibrutinib, Bendamustine Plus Rituximab (BR) and Ibrutinib Plus BR in Patients with Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): An Indirect Comparison of the RESONATE and HELIOS Trials","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Juravinski Cancer Centre","funders":"","keywords":"Medicine; Ibrutinib; Chemoimmunotherapy; Bendamustine; Internal medicine; Rituximab; Clinical endpoint; Ofatumumab; Oncology; Placebo; Progression-free survival; Chronic lymphocytic leukemia; Surgery; Clinical trial; Leukemia; Lymphoma; Chemotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01143252,0.001894221,0.003359226,0.0008922963,0.0002839297,0.001338726,0.001168209,0.001454419,0.004482721],"category_scores_gemma":[0.01564639,0.0006230272,0.007478252,0.0007643127,0.0009303537,0.00129852,0.00145153,0.00246909,0.0005081326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001029516,"about_ca_system_score_gemma":0.0007407308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006028124,"about_ca_topic_score_gemma":0.001179953,"domain_scores_codex":[0.9872133,0.01037654,0.0008670664,0.000702418,0.0005348777,0.0003057533],"domain_scores_gemma":[0.9880154,0.006835139,0.003255402,0.0007468542,0.0005686131,0.0005785266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.9072989,0.001428638,0.005800275,0.004603734,0.05339077,0.0000589451,0.0001698962,0.001867255,0.001338308,0.000504821,0.0007147975,0.02282357],"study_design_scores_gemma":[0.6863295,0.1872997,0.02901903,0.001266112,0.08226394,0.000244781,0.0002536489,0.003639415,0.002594439,0.002382553,0.004571892,0.0001349774],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9583283,0.02808707,0.002302518,0.0009554667,0.0008713,0.002754334,0.002427803,0.00006797832,0.004205213],"genre_scores_gemma":[0.990321,0.002866991,0.001993893,0.0005994007,0.0003514744,0.00207019,0.0009089142,0.00001546797,0.000872675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01143252,"threshold_uncertainty_score":0.0604617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09230312178758879,"score_gpt":0.3083665010327774,"score_spread":0.2160633792451886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}