{"id":"W2491072978","doi":"10.1152/ajprenal.00167.2016","title":"Acute kidney injury induces hallmarks of polycystic kidney disease","year":2016,"lang":"en","type":"article","venue":"American Journal of Physiology-Renal Physiology","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"PKD1; Autosomal dominant polycystic kidney disease; Polycystic kidney disease; Kidney; Wnt signaling pathway; Transgene; Genetically modified mouse; Acute kidney injury; Medicine; Stimulation; Kidney disease; Cancer research; Endocrinology; Internal medicine; Biology; Signal transduction; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002104759,0.0004397241,0.0005795048,0.0004756537,0.0002526319,0.0004308644,0.0001837392,0.0004278033,0.0009361744],"category_scores_gemma":[0.000182327,0.0001844111,0.0004560947,0.0002795593,0.0003663564,0.0003124496,0.0006044115,0.00108601,0.0002316581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002616734,"about_ca_system_score_gemma":0.0002759305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001980867,"about_ca_topic_score_gemma":0.0003532789,"domain_scores_codex":[0.9994754,0.00005877125,0.00007441109,0.0001198501,0.0001723805,0.00009913389],"domain_scores_gemma":[0.9996046,0.00002894205,0.0001431785,0.00004120625,0.00004678238,0.0001352159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001940981,0.00007862144,0.002212011,0.0001056228,0.00001396886,0.0002849342,0.00004026324,0.00002360797,0.9956633,0.0000789885,0.00004145854,0.001263135],"study_design_scores_gemma":[0.00003651989,0.001883204,0.1722069,0.00004000805,0.00007337297,0.004533005,0.0002059477,0.000521273,0.8157108,0.0002850657,0.00448023,0.00002369678],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908879,0.003127538,0.003567735,0.0001227749,0.0000543601,0.00007513859,0.0004545664,0.0001620428,0.001548015],"genre_scores_gemma":[0.9930093,0.002010195,0.002189986,0.00009520532,0.00003568055,0.0001208602,0.0008056456,0.00001899969,0.001714253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009361744,"threshold_uncertainty_score":0.003131807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004451816621862127,"score_gpt":0.2404097444130389,"score_spread":0.2359579277911767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}