{"id":"W249163298","doi":"10.2174/1874467208666150507093116","title":"Calcium Channel Signaling Complexes with Receptors and Channels","year":2015,"lang":"en","type":"review","venue":"Current Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Ion channel; R-type calcium channel; G protein-coupled receptor; Voltage-dependent calcium channel; T-type calcium channel; Calcium channel; Chemistry; N-type calcium channel; Voltage-gated ion channel; Calcium; Biophysics; Potassium channel; Calcium signaling; Cell biology; Calcium-activated potassium channel; Receptor; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002758831,0.0005725889,0.0009196529,0.000213935,0.0001078366,0.000038806,0.0002248674,0.0004042007,0.0000488292],"category_scores_gemma":[0.00002435222,0.0004769413,0.0002186975,0.0002233675,0.0001929819,0.000005928262,0.0002022527,0.0003545662,0.00002577913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005514568,"about_ca_system_score_gemma":0.0002806555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001705212,"about_ca_topic_score_gemma":2.966878e-7,"domain_scores_codex":[0.9977764,0.0003633772,0.0004207282,0.0007855221,0.0002174833,0.0004364651],"domain_scores_gemma":[0.9989218,0.00002216484,0.0003162017,0.0002362096,0.0002178659,0.0002858046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002647996,0.0003607573,0.000003602327,0.008756904,0.001274988,0.00005379965,0.0001361509,0.0006384201,0.008266805,0.0001375779,0.05727665,0.9228296],"study_design_scores_gemma":[0.0007435122,0.0003252775,1.035321e-7,0.0004881665,0.0005959257,0.0001233752,0.00001463878,0.00009709342,0.003464621,0.000016636,0.9935845,0.0005461313],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000292661,0.9883477,0.005032908,0.00003734713,0.005196128,0.0009142654,0.00004648555,0.00003908765,0.00009338772],"genre_scores_gemma":[0.0006636515,0.9942329,0.00006156968,0.0001227152,0.002160191,0.000272952,0.002081295,0.0001129573,0.0002917767],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9363078,"threshold_uncertainty_score":0.9997682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.080829290205642,"score_gpt":0.3746107722529638,"score_spread":0.2937814820473218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}