{"id":"W2493471747","doi":"10.1002/psc.2899","title":"On the synthesis of cyclodextrin–peptide conjugates by the Huisgen reaction","year":2016,"lang":"en","type":"article","venue":"Journal of Peptide Science","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"Agence Nationale de la Recherche; LABoratoires d’EXcellence ARCANE","keywords":"Chemistry; Conjugate; Click chemistry; Combinatorial chemistry; Peptide; Context (archaeology); Cyclodextrin; Macromolecule; Stereochemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001250435,0.00008399059,0.0001364721,0.00003829733,0.0001265498,0.00002527121,0.0005906468,0.00003753396,0.00008056674],"category_scores_gemma":[0.002039222,0.00003246398,0.0001749469,0.0001827316,0.0005551053,0.00001253768,0.00006268528,0.0000692504,0.00001080443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002482645,"about_ca_system_score_gemma":0.00007538588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001362201,"about_ca_topic_score_gemma":0.000003094736,"domain_scores_codex":[0.9989582,0.00005799384,0.0002943904,0.0001475675,0.0003851379,0.0001566744],"domain_scores_gemma":[0.9987267,0.0003456823,0.0003873112,0.0002804981,0.0001947729,0.0000650521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003087201,0.00002804202,0.0002833501,0.000001353731,0.00002732337,3.214796e-7,0.000006714778,0.000003160884,0.9869369,0.0001264244,0.0061118,0.006443783],"study_design_scores_gemma":[0.00007353612,0.00007726264,0.0006858857,0.00005297991,0.00002897774,0.00001334697,0.00006052243,0.000007696422,0.9858412,0.0002885818,0.01281414,0.0000559368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939246,0.0001765109,0.0001775396,0.003473124,0.00003804335,0.00003510401,0.00000777616,0.000001308941,0.002165957],"genre_scores_gemma":[0.9986343,0.0002602435,0.00005439769,0.0001513309,0.0001023474,0.000002009683,1.668772e-7,0.000004956501,0.0007902707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006702341,"threshold_uncertainty_score":0.2441286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007979755774669922,"score_gpt":0.2350292526014285,"score_spread":0.2270494968267586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}