{"id":"W2493491500","doi":"10.1016/j.peptides.2016.07.007","title":"Ultrashort cationic lipopeptides and lipopeptoids: Evaluation and mechanistic insights against epithelial cancer cells","year":2016,"lang":"en","type":"article","venue":"Peptides","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"DU145; Cancer cell; Apoptosis; Chemistry; Programmed cell death; Cancer; Biochemistry; Amphiphile; Cytotoxicity; Cancer research; Cell biology; Biology; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002728095,0.0002546669,0.0002956854,0.000107647,0.0003529993,0.00005497316,0.0001152085,0.0001773502,0.000428135],"category_scores_gemma":[0.0001011479,0.0001750217,0.00005285884,0.00007431464,0.000445307,0.0003128527,0.00008500083,0.0001252852,0.0001523155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007197349,"about_ca_system_score_gemma":0.00009877713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004471275,"about_ca_topic_score_gemma":0.0004745588,"domain_scores_codex":[0.9987067,0.0001548999,0.0002841289,0.0004534979,0.00006838219,0.0003323964],"domain_scores_gemma":[0.9992289,0.0002438309,0.0001348121,0.0002040518,0.0001437606,0.00004465995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004162632,0.00003463888,0.0007126559,0.00002395988,0.00009110265,9.578785e-7,0.0004396483,0.000004174911,0.9162032,0.0008005446,0.001154669,0.0804928],"study_design_scores_gemma":[0.001390014,0.0001456446,0.007368482,0.0003218611,0.00016238,0.00002066211,0.0004131914,0.00002453286,0.9772229,0.001969098,0.01048952,0.0004717625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936898,0.0037489,0.0001993932,0.0003528388,0.0005662774,0.0003928621,0.000110654,0.00007710329,0.0008622209],"genre_scores_gemma":[0.9910926,0.00553499,0.0001392764,0.0002246896,0.0001331697,0.00007766373,0.00003165567,0.00002828171,0.002737647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08002105,"threshold_uncertainty_score":0.7137179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01296217812018225,"score_gpt":0.2422402336813376,"score_spread":0.2292780555611554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}