{"id":"W2494695673","doi":"10.1083/jcb.201605090","title":"BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers","year":2016,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Eye Institute; National Heart, Lung, and Blood Institute; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Medical Research Council; National Institutes of Health; Canadian Institutes of Health Research; Wellcome; Université de Recherche Paris Sciences et Lettres; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Wellcome Trust; University of Pennsylvania; Labex CelTisPhyBio; Infrastructures en Biologie Santé et Agronomie; Centre National de la Recherche Scientifique","keywords":"Melanosome; Rab; Endosome; Cell biology; Endomembrane system; Lipid bilayer fusion; SNARE complex; Transport protein; Biology; Organelle; Chemistry; GTPase; Biochemistry; Membrane; Golgi apparatus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002918588,0.0001040197,0.0001649738,0.00003076933,0.00005705448,0.000004765378,0.0001188859,0.0001006799,0.00002259937],"category_scores_gemma":[0.00002831298,0.00005535517,0.00003926346,0.00002406717,0.0001137835,0.000003351862,0.00003252395,0.00005726264,0.000001480226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006436112,"about_ca_system_score_gemma":0.00002078763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002536354,"about_ca_topic_score_gemma":0.00002127883,"domain_scores_codex":[0.9993223,0.0001118832,0.0002433515,0.0001295862,0.0000565165,0.0001363656],"domain_scores_gemma":[0.9995237,0.00005978389,0.0001411625,0.0001284552,0.00004613685,0.0001007421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002308347,0.000008191335,0.00892509,0.000003374642,0.00005239632,0.00000421214,0.0001687302,0.000003166023,0.9876246,0.000007481608,0.00006066756,0.002911187],"study_design_scores_gemma":[0.000931916,0.0005580171,0.01722768,0.00002102974,0.00008734586,0.00007325803,0.00008131241,0.000006097811,0.9749933,0.0008273714,0.005074013,0.0001185935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939299,0.001346439,0.003863238,0.0004977196,0.0001650694,0.00006867779,0.00001969799,0.000002017887,0.000107191],"genre_scores_gemma":[0.998104,0.0009427586,0.0004198291,0.0001577978,0.0002074931,8.828812e-7,0.00001018174,0.000009072034,0.0001479754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0126313,"threshold_uncertainty_score":0.2257318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004806926958385819,"score_gpt":0.218473533737143,"score_spread":0.2136666067787572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}