{"id":"W2496068731","doi":"10.1158/1538-7445.am2016-850","title":"Abstract 850: Comprehensive genome and transcriptome structural analysis of a breast cancer cell line using single molecule sequencing","year":2016,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Chromothripsis; Structural variation; Copy number analysis; Breakpoint; Copy-number variation; Genome; Context (archaeology); Computational biology; Biology; Genome instability; Genetics; Cancer; Genomics; Breast cancer; Cancer genome sequencing; Gene; Chromosome; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002021576,0.0003666435,0.0003624859,0.0003259879,0.0003427836,0.0003248088,0.0002881157,0.0003756489,0.001297794],"category_scores_gemma":[0.0002097485,0.0001723471,0.0003101164,0.000591226,0.0001125718,0.0001420054,0.0001602135,0.0003942151,0.001020398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000300939,"about_ca_system_score_gemma":0.0002570577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003726933,"about_ca_topic_score_gemma":0.004810036,"domain_scores_codex":[0.9998056,0.00001888631,0.00001395674,0.00006098745,0.00008138335,0.00001920697],"domain_scores_gemma":[0.99988,0.00003351261,0.00001375153,0.00002143797,0.00003538881,0.00001599852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004154186,0.00001776699,0.0006619952,0.00002968911,0.00000883165,0.0000429307,0.000019788,0.0004661255,0.9955698,0.0000611275,0.0003779655,0.00270261],"study_design_scores_gemma":[0.00002168981,0.0003328886,0.0410282,0.00001136885,0.00006715976,0.0003468856,0.00007259831,0.03348413,0.9160613,0.0002127551,0.008328357,0.00003266865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8656409,0.0008573963,0.09340943,0.0002480477,0.00009880367,0.0002223742,0.0309821,0.003872102,0.004668735],"genre_scores_gemma":[0.7192759,0.0008285081,0.1942273,0.0002723565,0.00002342505,0.0003707074,0.07854837,0.0006906453,0.005762909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003726933,"threshold_uncertainty_score":0.007410467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06582348315489081,"score_gpt":0.3586367848213742,"score_spread":0.2928133016664834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}