{"id":"W2496768774","doi":"10.1021/acs.analchem.6b01900","title":"Kinetics of Proximity-Induced Intramolecular DNA Strand Displacement","year":2016,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Brock University","funders":"Canadian Institutes of Health Research; Alberta Health; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada","keywords":"Chemistry; DNA; Biophysics; Kinetics; Intramolecular force; A-DNA; Displacement (psychology); Stereochemistry; Biochemistry; Biology; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008700674,0.0001795461,0.0002182706,0.00001868045,0.00002141333,0.000008865054,0.0001755697,0.0001980494,0.0000211221],"category_scores_gemma":[0.0001686226,0.0001216636,0.0001658581,0.0001047433,0.0001811336,0.000003321481,0.0000875214,0.00006609916,0.000001843035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002024002,"about_ca_system_score_gemma":0.00002158425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001456935,"about_ca_topic_score_gemma":0.000001691939,"domain_scores_codex":[0.9988593,0.00002065203,0.0003037308,0.0003706449,0.0002025171,0.0002430974],"domain_scores_gemma":[0.9991812,0.00001636657,0.0001016263,0.0004569932,0.0001250506,0.0001187993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006537583,0.000124296,0.0002788044,0.00003051785,0.00009641318,0.000004290953,0.000001499597,5.312149e-7,0.996996,0.00004997333,0.0002975497,0.00205472],"study_design_scores_gemma":[0.0003685513,0.0001648182,0.0001185366,0.00003998963,0.0000801741,0.000008130896,0.00001036273,0.00002115152,0.9961747,0.0001671761,0.002652599,0.0001937973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854495,0.00004266382,0.01120889,0.0004558078,0.00001316776,0.0000831437,0.00002339268,0.00002467036,0.002698744],"genre_scores_gemma":[0.9977881,0.0000593251,0.0009175227,0.00006504069,0.0001068539,0.000004028294,0.00003480274,0.00001648316,0.001007844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01233858,"threshold_uncertainty_score":0.4961296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009653329196428105,"score_gpt":0.2671880871846258,"score_spread":0.2575347579881977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}