{"id":"W2496768774","doi":"10.1021/acs.analchem.6b01900","title":"Kinetics of Proximity-Induced Intramolecular DNA Strand Displacement","year":2016,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Brock University","funders":"Canadian Institutes of Health Research; Alberta Health; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada","keywords":"Chemistry; DNA; Biophysics; Kinetics; Intramolecular force; A-DNA; Displacement (psychology); Stereochemistry; Biochemistry; Biology; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007119651,0.0003319017,0.0003290523,0.000247535,0.0001763968,0.0004526303,0.0005882372,0.0003944713,0.002047532],"category_scores_gemma":[0.001960422,0.0002662351,0.0002122086,0.0002712092,0.0003895923,0.000746636,0.0003328396,0.001126253,0.0005618093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003910112,"about_ca_system_score_gemma":0.0003208416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005111605,"about_ca_topic_score_gemma":0.0005349768,"domain_scores_codex":[0.9993899,0.00007277825,0.00002997835,0.0001960805,0.0002306254,0.00008061429],"domain_scores_gemma":[0.9987632,0.0006765781,0.0001747193,0.00009799516,0.0002083625,0.00007923041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001443863,0.00006506381,0.0006273802,0.0001275649,0.00001676675,0.00006265628,0.0002054499,0.001075484,0.9860473,0.0008260442,0.0001571824,0.01064481],"study_design_scores_gemma":[0.000006289179,0.0001626899,0.0008609029,0.000005971922,0.00000641058,0.0000471544,0.00004163327,0.005165172,0.9920976,0.0001277924,0.001466637,0.00001181033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9148843,0.003009571,0.07326014,0.0002067725,0.00009301391,0.0001927016,0.0004827093,0.0006433648,0.007227322],"genre_scores_gemma":[0.9820954,0.000849676,0.01285941,0.00008112,0.000008511602,0.00009682274,0.0003078321,0.00004150996,0.00365967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002047532,"threshold_uncertainty_score":0.006849706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009653329196428105,"score_gpt":0.2671880871846258,"score_spread":0.2575347579881977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}