{"id":"W2497569195","doi":"10.1186/s13064-016-0068-8","title":"Dual leucine zipper kinase regulates expression of axon guidance genes in mouse neuronal cells","year":2016,"lang":"en","type":"article","venue":"Neural Development","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Compute Canada; Université de Sherbrooke","keywords":"Biology; Semaphorin; Axon guidance; Gene knockdown; Cell biology; KEGG; Leucine zipper; Gene; Erythropoietin-producing hepatocellular (Eph) receptor; Plexin; RNA interference; Gene expression profiling; Regulation of gene expression; Small hairpin RNA; Gene expression; Signal transduction; Genetics; Axon; Transcription factor; RNA; Receptor tyrosine kinase; Receptor; Transcriptome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000136003,0.0003866007,0.0002312894,0.0006002508,0.0001728023,0.0003331149,0.0002248499,0.0002857353,0.001122414],"category_scores_gemma":[0.00008303853,0.0002043463,0.0003668341,0.000250912,0.0002455235,0.0001722935,0.0002574695,0.0004617812,0.0005879023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006017903,"about_ca_system_score_gemma":0.0002877355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007831078,"about_ca_topic_score_gemma":0.001566127,"domain_scores_codex":[0.9997953,0.00001252909,0.00001757504,0.00007728035,0.00005795338,0.00003950808],"domain_scores_gemma":[0.9998679,0.00001321918,0.00006035839,0.00001282547,0.00001484879,0.00003078445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006139548,0.000007592375,0.0004636764,0.00002690424,0.000003966227,0.00002736159,0.000007913629,0.00003999083,0.9987147,0.00003386457,0.00002042255,0.0005922042],"study_design_scores_gemma":[0.00001992555,0.0001269739,0.02661555,0.00001342518,0.00003152192,0.000306728,0.00003863753,0.001247667,0.9684865,0.00008060367,0.003023386,0.000009022685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889875,0.00293226,0.003783701,0.00008108203,0.00003333209,0.00003590918,0.002455724,0.0002299802,0.001460537],"genre_scores_gemma":[0.9815722,0.00183932,0.00789766,0.0001153616,0.00001020208,0.0001404534,0.003246152,0.000116149,0.005062534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001122414,"threshold_uncertainty_score":0.004366279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03681022599277188,"score_gpt":0.2528923272070774,"score_spread":0.2160821012143055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}