{"id":"W2498089677","doi":"10.2147/blctt.s84157","title":"Waldenstr&amp;ouml;m macroglobulinemia: biology, genetics, and therapy","year":2016,"lang":"en","type":"review","venue":"Blood and Lymphatic Cancer Targets and Therapy","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Stephen's University","funders":"","keywords":"Ibrutinib; Waldenstrom macroglobulinemia; Bruton's tyrosine kinase; Medicine; Lymphoplasmacytic Lymphoma; Rituximab; Oncology; Lymphoma; Macroglobulinemia; CXCR4; Internal medicine; Germline mutation; Cancer research; Immunology; Leukemia; Chronic lymphocytic leukemia; Biology; Mutation; Tyrosine kinase; Genetics; Multiple myeloma; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003328818,0.0007422174,0.002123016,0.00019662,0.0001875098,0.00009292846,0.0001820779,0.0005849657,0.0004638976],"category_scores_gemma":[0.00002981423,0.0004288202,0.0002382444,0.0001685892,0.0006737959,0.00004756455,0.0001372323,0.0002097452,0.000012877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006116878,"about_ca_system_score_gemma":0.003555362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006218699,"about_ca_topic_score_gemma":0.00002684409,"domain_scores_codex":[0.9972367,0.0001509755,0.0006527964,0.000967082,0.0002806738,0.0007118299],"domain_scores_gemma":[0.9983208,0.00029889,0.0002641594,0.0005542753,0.000111203,0.0004506551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001158165,0.0001131493,0.0001563482,0.003325416,0.001235308,0.00004608295,0.0001218641,1.007642e-8,0.00005600818,0.00008862362,0.0004938384,0.9942476],"study_design_scores_gemma":[0.01883369,0.0004245151,0.00003007216,0.004807313,0.0004781899,0.0009563044,0.000008776453,0.00001031992,0.00004778128,0.0002766657,0.9736188,0.0005075909],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005905116,0.9914724,0.000007961374,0.0003416666,0.0002599964,0.00153596,0.0002023015,0.00005372033,0.0002208935],"genre_scores_gemma":[0.0004443828,0.9958816,0.0002214901,0.0004870822,0.001047613,0.0002842178,0.00008161808,0.0001172986,0.001434661],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.99374,"threshold_uncertainty_score":0.9998164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06055768449692186,"score_gpt":0.3826594748749941,"score_spread":0.3221017903780722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}