{"id":"W2498901811","doi":"10.1016/j.cmet.2016.07.018","title":"Empagliflozin’s Fuel Hypothesis: Not so Soon","year":2016,"lang":"en","type":"letter","venue":"Cell Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":129,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital; University of Alberta","funders":"","keywords":"Empagliflozin; Computational biology; Aeronautics; Medicine; Biology; Engineering; Diabetes mellitus; Endocrinology; Type 2 diabetes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00313583,0.0007482553,0.001803068,0.0006042729,0.002579757,0.003896468,0.001496951,0.03266365,0.006627462],"category_scores_gemma":[0.0184487,0.0004409851,0.001017593,0.0004526542,0.004438468,0.006008532,0.002281302,0.04563043,0.004145056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003429019,"about_ca_system_score_gemma":0.002348473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001979687,"about_ca_topic_score_gemma":0.002974594,"domain_scores_codex":[0.9982395,0.0006158265,0.0002004783,0.0002886959,0.0004523427,0.0002030908],"domain_scores_gemma":[0.9935938,0.00397674,0.0004302863,0.0002159466,0.000841221,0.0009419898],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002674437,0.0001071687,0.0009060552,0.0001510333,0.00008154365,0.004258676,0.0002057049,0.0001056222,0.0003307309,0.01786524,0.9295862,0.04613463],"study_design_scores_gemma":[0.0005273671,0.0001729596,0.0009012104,0.0007138074,0.00009639956,0.004260924,0.0007243602,0.0005097675,0.0004381293,0.08030871,0.9112422,0.0001042195],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0003044546,0.00344458,0.0001066071,0.9845697,0.01012742,0.000003484126,0.00002015407,0.000009444465,0.001414118],"genre_scores_gemma":[0.008515959,0.005336115,0.0003377636,0.8923338,0.08915416,0.0000244951,0.00003226998,0.00001998593,0.004245418],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03266365,"threshold_uncertainty_score":0.02487946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02296589570410121,"score_gpt":0.2250640468878559,"score_spread":0.2020981511837547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}