{"id":"W2499808140","doi":"10.1016/j.neuro.2016.07.012","title":"Single and repeated exposures to the volatile anesthetic isoflurane do not impair operant performance in aged rats","year":2016,"lang":"en","type":"article","venue":"NeuroToxicology","topic":"Anesthesia and Neurotoxicity Research","field":"Neuroscience","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Isoflurane; Anesthesia; Hippocampus; Postoperative cognitive dysfunction; Anesthetic; Hippocampal formation; Perioperative; Medicine; Cognition; Volatile anesthetic; Psychology; Neuroscience; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004520421,0.0002459314,0.0003105814,0.0002264738,0.0002745081,0.00007958136,0.0005909576,0.0001215969,0.0001339677],"category_scores_gemma":[0.0009023581,0.0001412982,0.0000494856,0.0005135078,0.0003800926,0.0001914908,0.000205738,0.0003334238,0.0001729889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004012227,"about_ca_system_score_gemma":0.00005799826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001041989,"about_ca_topic_score_gemma":0.00004286388,"domain_scores_codex":[0.9968507,0.0009495997,0.0003708118,0.0007804628,0.0003475873,0.0007008935],"domain_scores_gemma":[0.998107,0.001028012,0.00007124568,0.0005747591,0.00003317271,0.0001857888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005180342,0.000143472,0.02158478,0.00001261552,9.638655e-7,0.000361867,0.0003247675,0.00001426345,0.971175,0.00005745938,0.000190669,0.005616125],"study_design_scores_gemma":[0.0008610917,0.00223783,0.1435404,0.00003336576,0.000002916635,0.0008023879,0.00001207523,0.0001952211,0.845457,0.00002003086,0.006648615,0.0001890682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885531,0.00001703984,0.000007355324,0.009168698,0.0001049215,0.001814865,0.000004604973,0.00008780486,0.0002416123],"genre_scores_gemma":[0.9931182,0.00008563347,0.00001132639,0.00548756,0.0000470894,0.0003862458,2.365474e-7,0.00003842869,0.000825231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.125718,"threshold_uncertainty_score":0.5761972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04469313129661661,"score_gpt":0.2789123619821623,"score_spread":0.2342192306855457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}