{"id":"W2500359689","doi":"10.1021/bk-2012-1119.ch004","title":"Glyconanoparticles for Gene Delivery","year":2012,"lang":"en","type":"book-chapter","venue":"ACS symposium series","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Alberta Glycomics Centre","funders":"","keywords":"Gene delivery; Nanotechnology; Biocompatibility; Nucleic acid; Colloidal gold; Nanoparticle; Genetic enhancement; Liposome; Chemistry; In vivo; Drug delivery; Materials science; Gene; Biology; Biochemistry; Biotechnology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006790909,0.0003227284,0.0002687419,0.00003416002,0.00009487716,0.00004454187,0.0002190377,0.000433016,0.00007942649],"category_scores_gemma":[0.00001019783,0.0003231015,0.0002097049,0.000008735655,0.0001146568,0.00001136239,0.000171025,0.00008115962,0.00006781919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001483216,"about_ca_system_score_gemma":0.0001057169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004657812,"about_ca_topic_score_gemma":0.00003633534,"domain_scores_codex":[0.9989046,0.000009890283,0.0002565231,0.0004035136,0.0001073311,0.0003181206],"domain_scores_gemma":[0.999069,0.00001188194,0.0001243922,0.0004708036,0.0002301193,0.00009383351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002003654,0.00001839054,0.00002931251,0.00004687659,0.0002032174,0.000004695609,0.00003969845,0.000003506273,0.9853454,0.00293679,0.009316319,0.001855438],"study_design_scores_gemma":[0.0001306498,0.0002674593,0.000009364633,0.0000243294,0.00007780901,0.00003389086,0.00001328303,2.723209e-7,0.5569236,0.000366251,0.441882,0.0002711098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.6472173,0.110105,0.0004440126,0.001583746,0.00354809,0.00175647,0.001696143,0.0001471536,0.2335021],"genre_scores_gemma":[0.1886051,0.01969072,0.0008934501,0.000843161,0.002342493,0.0001084398,0.00214549,0.0001607568,0.7852104],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.5517083,"threshold_uncertainty_score":0.9999221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01486961511598247,"score_gpt":0.2210789417428398,"score_spread":0.2062093266268573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}