{"id":"W2501122491","doi":"10.1016/j.tig.2016.07.001","title":"Epigenetics ELSI: Darker Than You Think?","year":2016,"lang":"en","type":"letter","venue":"Trends in Genetics","topic":"Birth, Development, and Health","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre","funders":"Canadian Institutes of Health Research","keywords":"Biology; Epigenetics; Epigenesis; Genetics; Evolutionary biology; Cognitive science; DNA methylation; Gene; Gene expression; Psychology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003281976,0.0006241176,0.0009154758,0.0008026898,0.00008575606,0.00003068632,0.0004130542,0.001676625,0.001222079],"category_scores_gemma":[0.00002823463,0.0004932808,0.0002070921,0.0004051869,0.0001850304,0.00002103238,0.0001492674,0.002045396,0.0002977492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003150053,"about_ca_system_score_gemma":0.0007251738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003090396,"about_ca_topic_score_gemma":0.0001208177,"domain_scores_codex":[0.9962519,0.000122616,0.0008643466,0.0008106446,0.0008006602,0.001149784],"domain_scores_gemma":[0.9980763,0.00007567782,0.0002782777,0.001205251,0.000123423,0.000241082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004438416,0.00005214603,0.01519845,0.0003050029,0.0001093567,0.00052405,0.0006053832,5.981741e-7,0.00004373016,0.0001957727,0.9103833,0.07253783],"study_design_scores_gemma":[0.001498437,0.0002610374,0.05975094,0.0004255496,0.0001476226,0.00006948697,0.00002261995,0.00001472242,0.0002407735,0.002955933,0.9340289,0.0005839446],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.005696462,0.006534766,0.0001727439,0.8251541,0.003176173,0.0006255672,0.0002761447,0.0002224189,0.1581416],"genre_scores_gemma":[0.00487196,0.1505023,0.01230898,0.7620015,0.01341924,0.00005909655,0.001391136,0.0004013337,0.05504446],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1439676,"threshold_uncertainty_score":0.9997519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04692961212804202,"score_gpt":0.3226491540178319,"score_spread":0.2757195418897899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}