{"id":"W2501981640","doi":"10.1093/jac/dkw246","title":"Surotomycin versus vancomycin for<i>Clostridium difficile</i>infection: Phase 2, randomized, controlled, double-blind, non-inferiority, multicentre trial","year":2016,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Foothills Medical Centre; University of Calgary; McMaster University; Hamilton Regional Laboratory Medicine Program; Royal Jubilee Hospital; St. Joseph’s Healthcare Hamilton; Island Health","funders":"Viropharma; Merck","keywords":"Medicine; Vancomycin; Clostridium difficile; Adverse effect; Internal medicine; Antibiotics; Randomized controlled trial; Incidence (geometry); Clinical trial; Surgery; Diarrhea; Antibacterial agent; Gastroenterology; Anesthesia; Staphylococcus aureus; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002256637,0.00208785,0.002988703,0.0004461893,0.0004155251,0.001395972,0.0009763806,0.002331574,0.007117623],"category_scores_gemma":[0.002436299,0.0007148171,0.002004421,0.0004705987,0.001071326,0.001186834,0.0003719017,0.002323759,0.0008597656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007995501,"about_ca_system_score_gemma":0.00140208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005519468,"about_ca_topic_score_gemma":0.001439492,"domain_scores_codex":[0.9987605,0.00071505,0.00008180559,0.0002106476,0.00009539648,0.0001366815],"domain_scores_gemma":[0.998562,0.0004429359,0.0005152369,0.00009530697,0.0001092665,0.0002752515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9846742,0.004355735,0.0001448758,0.001052929,0.000616051,0.00002046109,0.00002944083,0.0001376709,0.002347841,0.000068579,0.0004075076,0.006144634],"study_design_scores_gemma":[0.941259,0.05699224,0.0004746921,0.00005003843,0.0002911895,0.00002015285,0.00001019424,0.0002253421,0.0003032081,0.00007245142,0.0002915844,0.000009913276],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724,0.00973148,0.001478508,0.001122423,0.001200486,0.00973361,0.001467604,0.0002342667,0.00263173],"genre_scores_gemma":[0.9735538,0.005629346,0.003373649,0.00158389,0.0009772322,0.009916269,0.001059045,0.00004760149,0.003859236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007117623,"threshold_uncertainty_score":0.02381086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04132298690798683,"score_gpt":0.3625863414447916,"score_spread":0.3212633545368048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}