{"id":"W2502183409","doi":"10.1200/jco.2015.33.7_suppl.3","title":"ASCENDE-RT*: A multicenter, randomized trial of dose-escalated external beam radiation therapy (EBRT-B) versus low-dose-rate brachytherapy (LDR-B) for men with unfavorable-risk localized prostate cancer.","year":2015,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; BC Cancer Agency","funders":"","keywords":"Medicine; Prostate cancer; Brachytherapy; Clinical endpoint; Urology; Randomized controlled trial; Androgen deprivation therapy; External beam radiotherapy; Goserelin; Internal medicine; Radiation therapy; Cancer; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01093003,0.0003424552,0.003441736,0.0002472523,0.00008419403,0.00003105791,0.0002558616,0.0004565764,0.00007586495],"category_scores_gemma":[0.0032771,0.0001948086,0.0009143705,0.0003065187,0.0006250394,0.0002510292,0.0000293089,0.001025277,0.000004059678],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005292007,"about_ca_system_score_gemma":0.005860985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003202551,"about_ca_topic_score_gemma":0.00004257245,"domain_scores_codex":[0.9929975,0.002032637,0.003209839,0.0003840521,0.0008422617,0.0005337211],"domain_scores_gemma":[0.9880567,0.005061839,0.004067308,0.0002983357,0.001765075,0.0007507898],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8554539,0.003518256,0.004529553,0.00004895813,0.003088351,0.0001221945,0.0005435856,0.0002633387,0.0004586737,0.000009385688,0.0008764916,0.1310873],"study_design_scores_gemma":[0.9176358,0.06628247,0.00275723,0.000264177,0.001028985,0.00002086814,0.0001799732,0.004154852,0.001523244,0.000242794,0.005728289,0.0001813304],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824827,0.00560973,0.0006574892,0.003345059,0.002296058,0.005249916,0.00004389031,0.00002508688,0.0002901148],"genre_scores_gemma":[0.9437612,0.04914336,0.003085361,0.0004545137,0.002086882,0.0003455711,0.00004016939,0.00008493599,0.0009979876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.130906,"threshold_uncertainty_score":0.9997749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1181076976637788,"score_gpt":0.4752221609193588,"score_spread":0.35711446325558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}