{"id":"W2502752511","doi":"10.1152/ajpgi.00022.2016","title":"Preterm infant gut microbiota affects intestinal epithelial development in a humanized microbiome gnotobiotic mouse model","year":2016,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institute of Child Health and Human Development; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; University of Chicago","keywords":"Paneth cell; Crypt; Biology; Enterocyte; Goblet cell; Microbiology; Gut flora; Microbiome; LGR5; Mucin 2; Stem cell; Ileum; Immunology; Enteroendocrine cell; Necrotizing enterocolitis; Cell biology; Small intestine; Epithelium; Bioinformatics; Internal medicine; Medicine; Genetics; Gene expression; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006671428,0.0008014354,0.0005536429,0.0009550329,0.0003071158,0.0006424951,0.0004433342,0.001041137,0.00209107],"category_scores_gemma":[0.0003752425,0.0004650135,0.0006562549,0.0003376496,0.0005415141,0.0005726481,0.000587429,0.001586187,0.0004936574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004064578,"about_ca_system_score_gemma":0.0003681672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004807081,"about_ca_topic_score_gemma":0.0005693633,"domain_scores_codex":[0.999409,0.0001277817,0.00006821976,0.0001689675,0.000138252,0.00008785291],"domain_scores_gemma":[0.9995471,0.0000503522,0.0001734083,0.00006979593,0.00003895216,0.0001204232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001586522,0.0004870934,0.001564755,0.000148005,0.00002481942,0.0007468623,0.0001070728,0.0001289471,0.9909277,0.0002138235,0.0001195307,0.003944789],"study_design_scores_gemma":[0.0002933641,0.009959666,0.04360687,0.0001506756,0.0003261669,0.007253344,0.0005359114,0.00376532,0.9239199,0.0005380216,0.009595323,0.00005543114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907765,0.001852253,0.004891085,0.0002396199,0.00004965108,0.0001013162,0.0007977524,0.0001786824,0.00111316],"genre_scores_gemma":[0.9826936,0.002919052,0.007405348,0.0002211062,0.00002529681,0.0003847813,0.001328466,0.00007752333,0.004944777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00209107,"threshold_uncertainty_score":0.00699538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007367606034790091,"score_gpt":0.2250644345797773,"score_spread":0.2176968285449872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}