{"id":"W2502752511","doi":"10.1152/ajpgi.00022.2016","title":"Preterm infant gut microbiota affects intestinal epithelial development in a humanized microbiome gnotobiotic mouse model","year":2016,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institute of Child Health and Human Development; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; University of Chicago","keywords":"Paneth cell; Crypt; Biology; Enterocyte; Goblet cell; Microbiology; Gut flora; Microbiome; LGR5; Mucin 2; Stem cell; Ileum; Immunology; Enteroendocrine cell; Necrotizing enterocolitis; Cell biology; Small intestine; Epithelium; Bioinformatics; Internal medicine; Medicine; Genetics; Gene expression; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003032564,0.0004309373,0.0007905272,0.0002509847,0.000108349,0.00001343152,0.0004247183,0.00008596954,0.00002229269],"category_scores_gemma":[0.0001230366,0.0003023827,0.0001710486,0.0001409869,0.001053123,0.00002222255,0.0003097443,0.0003343285,0.00001332083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008220499,"about_ca_system_score_gemma":0.0004049667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004598959,"about_ca_topic_score_gemma":0.00004724373,"domain_scores_codex":[0.9975903,0.0003041611,0.0006940516,0.0006040471,0.00008755176,0.0007198991],"domain_scores_gemma":[0.9984043,0.0001124012,0.0007522168,0.0002903549,0.0002182347,0.0002225012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001611509,0.0002251314,0.001644138,0.00005918404,0.00006043821,0.0000152582,0.0001383782,0.0000414934,0.9941288,0.00003841617,0.0001698847,0.00186736],"study_design_scores_gemma":[0.006562532,0.01150291,0.4159086,0.001036968,0.00007978718,0.005363281,0.000199115,0.0001906898,0.556922,0.0002754845,0.0008582207,0.001100394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983577,0.0001418459,0.001001846,0.0001434944,0.00007668525,0.0002231767,0.00003350804,0.00001124936,0.0000104851],"genre_scores_gemma":[0.9815833,0.0001529922,0.01744901,0.0004203508,0.0002166914,0.000008672385,0.00002254019,0.00003741323,0.0001090622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4372068,"threshold_uncertainty_score":0.9999428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007367606034790091,"score_gpt":0.2250644345797773,"score_spread":0.2176968285449872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}