{"id":"W2502754259","doi":"10.1093/carcin/bgw079","title":"miR-200b induces cell cycle arrest and represses cell growth in esophageal squamous cell carcinoma","year":2016,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Cancer research; Cyclin-dependent kinase 2; Wnt signaling pathway; Cyclin-dependent kinase 1; Cell cycle; Biology; Cell growth; Cell cycle checkpoint; Apoptosis; Cancer; Cyclin-dependent kinase; microRNA; G1 phase; Signal transduction; Internal medicine; Cell biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001217141,0.0002578741,0.0002025373,0.0001027131,0.00007281597,0.00002719757,0.0002217876,0.0002281484,0.00003503174],"category_scores_gemma":[0.00004739741,0.0002204149,0.00008827041,0.000124098,0.0001095272,0.00001253562,0.0001707879,0.00005229382,0.00001998769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003966432,"about_ca_system_score_gemma":0.0000999485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000128273,"about_ca_topic_score_gemma":0.00003250769,"domain_scores_codex":[0.9984213,0.0001129175,0.0002786746,0.000670197,0.0001452064,0.0003716683],"domain_scores_gemma":[0.9991018,0.00004255454,0.0001192073,0.0004732786,0.00008846632,0.0001747177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005503382,0.00009655462,0.1516559,0.0001085979,0.000003243347,0.00002496151,0.000051541,0.00001050387,0.8472537,0.000003575704,0.0005122203,0.0002241302],"study_design_scores_gemma":[0.0008467098,0.0000649437,0.2858683,0.000007280013,0.0000248227,0.00000445378,0.00003212866,0.000006028793,0.7127259,0.00003016992,0.0001767337,0.000212512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900764,0.008272845,0.00005938606,0.00006928448,0.0001359587,0.0002462906,0.00006502261,0.00001732667,0.001057502],"genre_scores_gemma":[0.9988405,0.0001512867,0.0001472354,0.00007134979,0.0002149293,0.00003912557,0.00004607872,0.00004939202,0.0004400757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1345278,"threshold_uncertainty_score":0.8988261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007454244056866075,"score_gpt":0.2094249296432191,"score_spread":0.201970685586353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}