{"id":"W2502754259","doi":"10.1093/carcin/bgw079","title":"miR-200b induces cell cycle arrest and represses cell growth in esophageal squamous cell carcinoma","year":2016,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Cancer research; Cyclin-dependent kinase 2; Wnt signaling pathway; Cyclin-dependent kinase 1; Cell cycle; Biology; Cell growth; Cell cycle checkpoint; Apoptosis; Cancer; Cyclin-dependent kinase; microRNA; G1 phase; Signal transduction; Internal medicine; Cell biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007506717,0.0002032238,0.0003112413,0.0003058381,0.000165746,0.0002345744,0.0001132157,0.0001936169,0.001297428],"category_scores_gemma":[0.00009324804,0.0001417703,0.000197183,0.0001879316,0.0001185506,0.00008044745,0.0001552097,0.0003480167,0.0006865351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002378388,"about_ca_system_score_gemma":0.0001994349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008208061,"about_ca_topic_score_gemma":0.001096828,"domain_scores_codex":[0.99991,0.00001208342,0.00001013364,0.00001575195,0.00003253071,0.00001953292],"domain_scores_gemma":[0.9999603,0.000006080675,0.000006301886,0.000006852942,0.000006478527,0.00001399829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001133327,0.00004793313,0.000264836,0.00003007846,0.000004702259,0.00007514995,0.00001308874,0.00003297146,0.9975921,0.00005247974,0.0001087815,0.001664541],"study_design_scores_gemma":[0.00004000407,0.000516974,0.01429579,0.000008792867,0.00001731569,0.0004822286,0.00004802201,0.001472929,0.9768429,0.00005523363,0.006213962,0.000005836764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918464,0.002536356,0.001367995,0.0000891102,0.00005313812,0.00004682085,0.0005860568,0.0001335683,0.003340592],"genre_scores_gemma":[0.9938451,0.0009110393,0.001096611,0.00008815001,0.00000692439,0.00006607579,0.0009914649,0.00002303769,0.002971602],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001297428,"threshold_uncertainty_score":0.004340291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007454244056866075,"score_gpt":0.2094249296432191,"score_spread":0.201970685586353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}