{"id":"W2503158277","doi":"10.1016/j.molcel.2016.06.030","title":"Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity","year":2016,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Coenzyme Q10 studies and effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"U.S. National Library of Medicine; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institute on Aging; Fondation pour la Recherche Médicale; École Polytechnique Fédérale de Lausanne; Labex; Institute of Genetics; Michigan Economic Development Corporation; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; U.S. Department of Energy; Agence Nationale de la Recherche; European Research Council; National Science Foundation","keywords":"Biology; Ataxia; Cerebellar ataxia; Kinase; Cell biology; Genetics; Neuroscience","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001220824,0.0001917812,0.0001992212,0.00002116859,0.00007311412,0.000008514201,0.0001379604,0.0001146099,0.00001522476],"category_scores_gemma":[0.00005471451,0.0001442591,0.0001020314,0.00008510024,0.0001814749,0.000004761388,0.0002672582,0.000049127,0.000008461256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001035927,"about_ca_system_score_gemma":0.00003326989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006615646,"about_ca_topic_score_gemma":0.00002514916,"domain_scores_codex":[0.9989296,0.00006973492,0.0001472128,0.0004157003,0.0001421515,0.0002955634],"domain_scores_gemma":[0.9993109,0.00002384045,0.00009377878,0.0004363806,0.00006448744,0.00007067684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000748313,0.00008624853,0.003092413,0.00006666926,0.00002341651,0.00002819221,0.00003047566,0.000003934637,0.9903063,0.0001337795,0.004977811,0.001175927],"study_design_scores_gemma":[0.0007642448,0.0003806833,0.00158506,0.00001937949,0.00003001469,0.000009303195,0.00001490312,0.000004605169,0.965137,0.00007421443,0.03176589,0.0002147177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745194,0.004633721,0.01921234,0.0001819309,0.00007603609,0.0001726967,0.00003187837,0.0000100413,0.001162013],"genre_scores_gemma":[0.9980887,0.0007775623,0.0006261002,0.0001195755,0.000042934,0.000009649067,0.000007294107,0.00002443366,0.0003037388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02678808,"threshold_uncertainty_score":0.5882714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007376333755932929,"score_gpt":0.2283852467329178,"score_spread":0.2210089129769849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}