{"id":"W2503659988","doi":"10.1111/1756-185x.12901","title":"Efficacy and safety of tofacitinib in patients with active rheumatoid arthritis: review of key Phase 2 studies","year":2016,"lang":"en","type":"review","venue":"International Journal of Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"Pfizer","keywords":"Tofacitinib; Medicine; Janus kinase inhibitor; Rheumatoid arthritis; Safety profile; Janus kinase; Internal medicine; Methotrexate; Adverse effect; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001902987,0.0008593254,0.002651139,0.002737774,0.0002625783,0.001077735,0.001256054,0.000889687,0.00409587],"category_scores_gemma":[0.003330098,0.0003603909,0.002084063,0.002706564,0.0003096531,0.0009109053,0.0005089665,0.0009030849,0.0005669006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000613215,"about_ca_system_score_gemma":0.001717509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001015363,"about_ca_topic_score_gemma":0.002076822,"domain_scores_codex":[0.9993566,0.0001337626,0.0002104577,0.00008860057,0.0001794306,0.00003119616],"domain_scores_gemma":[0.9978724,0.001321999,0.0004135978,0.00002800485,0.0003175862,0.00004635998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0004799373,0.00007492876,0.0004262386,0.2067471,0.001159018,0.0001761113,0.0001035375,0.0003007015,0.001165027,0.0006012201,0.01158773,0.7771784],"study_design_scores_gemma":[0.0005153893,0.001282952,0.007228783,0.1996293,0.01488874,0.004217727,0.0003275797,0.0003664307,0.002062609,0.002169338,0.7672125,0.00009868614],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000164008,0.9993957,0.00003885159,0.00008628311,0.0000396996,0.00001202508,0.00003480973,0.000002626921,0.0002259877],"genre_scores_gemma":[0.001182126,0.9984303,0.0001050743,0.0001110533,0.00004111735,0.00001362104,0.00004302647,0.000001004783,0.00007278094],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00409587,"threshold_uncertainty_score":0.01370209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02389808539371753,"score_gpt":0.370862223058146,"score_spread":0.3469641376644285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}