{"id":"W2503893926","doi":"10.1182/blood.v126.23.56.56","title":"PRM-151 in Myelofibrosis: Durable Efficacy and Safety at 72 Weeks","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Myelofibrosis; Medicine; Bone marrow; Fibrosis; Internal medicine; Essential thrombocythemia; Gastroenterology; Ruxolitinib; Surgery; Polycythemia vera","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004115881,0.0003406685,0.00073262,0.0001329524,0.0001577121,0.0002676234,0.0002923442,0.0004244328,0.00173756],"category_scores_gemma":[0.0002704719,0.0001233489,0.0004122751,0.0001240556,0.0002263776,0.0002942628,0.0001344772,0.0009769789,0.000457421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002315212,"about_ca_system_score_gemma":0.0002695501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001933506,"about_ca_topic_score_gemma":0.00048906,"domain_scores_codex":[0.9998982,0.00003100187,0.000008830655,0.00002199654,0.00001415486,0.00002578537],"domain_scores_gemma":[0.9998783,0.0000213678,0.00003075599,0.00001821393,0.000008828021,0.00004256478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1428401,0.01474582,0.01168512,0.001020622,0.0005569363,0.001251382,0.0002763755,0.003128638,0.2552696,0.0006020108,0.007132993,0.5614905],"study_design_scores_gemma":[0.1262976,0.6374234,0.09991536,0.0001737518,0.0007557583,0.006210678,0.0001183851,0.003793329,0.1060926,0.0004919827,0.01861244,0.0001146587],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936487,0.003999724,0.0004308612,0.0001784458,0.00003731214,0.0001344063,0.0002511188,0.00008506083,0.001234353],"genre_scores_gemma":[0.9972245,0.0007767757,0.0005539455,0.0002036645,0.00003386184,0.00008902715,0.0004840385,0.000008002052,0.0006262024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00173756,"threshold_uncertainty_score":0.005812705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02258450449944384,"score_gpt":0.2630835879488786,"score_spread":0.2404990834494347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}