{"id":"W2504681679","doi":"10.1093/cid/ciw496","title":"Ribavirin-Free Regimen With Sofosbuvir and Velpatasvir Is Associated With High Efficacy and Improvement of Patient-Reported Outcomes in Patients With Genotypes 2 and 3 Chronic Hepatitis C: Results From Astral-2 and -3 Clinical Trials","year":2016,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Hepatitis C virus research","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute on Drug Abuse","keywords":"Medicine; Sofosbuvir; Ribavirin; Regimen; Internal medicine; Hepatitis C; Adverse effect; Hepatitis C virus; Gastroenterology; Surgery; Immunology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001935411,0.000391111,0.001178281,0.0002118971,0.0002382449,0.0005962279,0.000278665,0.000503231,0.001516541],"category_scores_gemma":[0.001646657,0.0001684564,0.001222026,0.0003488594,0.0004200375,0.0004295637,0.0002419547,0.000983611,0.0002038891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002339671,"about_ca_system_score_gemma":0.0003627942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002813825,"about_ca_topic_score_gemma":0.0007557991,"domain_scores_codex":[0.9991153,0.0005139515,0.00009865977,0.00008042245,0.000134633,0.00005711487],"domain_scores_gemma":[0.9986634,0.0003738996,0.0005326968,0.0000987004,0.00008668646,0.0002445648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6923012,0.01217843,0.05131197,0.001973565,0.006574709,0.0001123545,0.000235684,0.0009870833,0.008133496,0.0001468429,0.002159706,0.2238849],"study_design_scores_gemma":[0.2910254,0.3088212,0.384625,0.000488871,0.004591737,0.0005596901,0.0002077537,0.001613306,0.002670637,0.0003063663,0.005006677,0.00008324054],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905148,0.007618964,0.0001083778,0.0002316609,0.00006923088,0.0001705935,0.0002263991,0.00002343528,0.001036619],"genre_scores_gemma":[0.9962671,0.00208556,0.0003214763,0.0003747883,0.0001073423,0.0001470449,0.0004463269,0.000005505706,0.0002447179],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001935411,"threshold_uncertainty_score":0.01023555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04126156857226808,"score_gpt":0.3669616359279809,"score_spread":0.3257000673557128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}