{"id":"W2505368404","doi":"10.1016/j.mce.2016.07.017","title":"Adipocyte-secreted chemerin is processed to a variety of isoforms and influences MMP3 and chemokine secretion through an NFkB-dependent mechanism","year":2016,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Dalhousie University","keywords":"Chemerin; Adipokine; Adipocyte; Paracrine signalling; Endocrinology; Adipose tissue; Internal medicine; Chemokine; Cell biology; Chemistry; Biology; Inflammation; Leptin; Medicine; Obesity; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008633783,0.0002300805,0.000470758,0.00009471545,0.00005829659,0.00001306773,0.00007644905,0.0001427412,0.0000983409],"category_scores_gemma":[0.00004969027,0.0001630571,0.00004061101,0.0001177276,0.0001808831,0.0001744611,0.0001166442,0.0001133983,0.000004175612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001153087,"about_ca_system_score_gemma":0.00004287641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001367768,"about_ca_topic_score_gemma":0.000006519052,"domain_scores_codex":[0.9986322,0.00003737645,0.0002834798,0.0004888255,0.0001874125,0.0003706963],"domain_scores_gemma":[0.9992936,0.00001628992,0.00009346355,0.0002832036,0.0001022879,0.0002111412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001870499,0.00005270538,0.0006876988,0.0001411191,0.000112896,0.0001120213,0.001027324,1.170712e-7,0.9789168,0.008365419,0.000005266455,0.01039158],"study_design_scores_gemma":[0.002303042,0.0008464972,0.002008509,0.00005976714,0.0002311374,0.0003474356,0.0002299362,0.00002246274,0.9859176,0.003401874,0.004424171,0.0002075719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777639,0.003674003,0.01672785,0.001044944,0.00004666713,0.0004321871,0.00001120985,0.00004179014,0.0002574349],"genre_scores_gemma":[0.9960929,0.001200867,0.001448653,0.0009076035,0.00003855889,0.00003569564,0.00001528185,0.00002704376,0.0002334063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01832898,"threshold_uncertainty_score":0.6649277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01243431920417777,"score_gpt":0.2603778178008672,"score_spread":0.2479434985966894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}