{"id":"W2505716482","doi":"10.18632/oncotarget.10731","title":"miR-28 modulates exhaustive differentiation of T cells through silencing programmed cell death-1 and regulating cytokine secretion","year":2016,"lang":"en","type":"article","venue":"Oncotarget","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"Gene silencing; microRNA; FOXP3; T cell; Cell biology; Cancer research; Biology; Transfection; Cell culture; Molecular biology; Immunology; Immune system; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001201362,0.0001566475,0.0002221449,0.00006517723,0.0001188784,0.00001032799,0.00005746896,0.0001808015,0.0006598589],"category_scores_gemma":[0.00003448406,0.0001127547,0.00006653248,0.00006785191,0.00007698254,0.0002523998,0.00004407448,0.0001181948,0.00007735498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006315667,"about_ca_system_score_gemma":0.00001600422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001205108,"about_ca_topic_score_gemma":0.000004309672,"domain_scores_codex":[0.999061,0.00009384493,0.0003257596,0.0002554152,0.00004112111,0.0002228048],"domain_scores_gemma":[0.9993398,0.000103238,0.0002749126,0.0001540323,0.0001137097,0.00001430484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001673414,0.00008836115,0.006533482,0.00003379746,0.00004447538,2.892776e-7,0.0006197662,0.000005591163,0.9903984,0.0001639318,0.0006881547,0.001256427],"study_design_scores_gemma":[0.001306093,0.0002601385,0.02014157,0.0001118096,0.00004260814,0.000007129252,0.0003012707,0.0001058919,0.9727772,0.0002667559,0.004533478,0.0001460322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921035,0.0003967714,0.004975901,0.0001463196,0.001146483,0.0002308636,0.000008423282,0.00006071649,0.0009309833],"genre_scores_gemma":[0.9939305,0.0001175426,0.0005694474,0.00003198551,0.00003704711,0.00001556581,0.0001137028,0.00001640239,0.00516784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01762117,"threshold_uncertainty_score":0.7224992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01223388884471371,"score_gpt":0.2264612014492068,"score_spread":0.2142273126044931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}