{"id":"W2506511086","doi":"10.3233/hab-160294","title":"A novel modified vaccination technique produces IgG antibodies that cause complement-mediated lysis of multiple myeloma cells carrying CD38 antigen","year":2016,"lang":"en","type":"article","venue":"Human Antibodies","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Lytic cycle; Immune system; Adjuvant; Antigen; Antibody; Lysis; In vitro; CD38; Immunology; Chemistry; Molecular biology; Biology; Microbiology; Virology; Virus; Biochemistry; Cell biology; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003399201,0.0003074353,0.0004277116,0.0002097723,0.0002447736,0.00003734896,0.0002821992,0.00014678,0.00003687729],"category_scores_gemma":[0.0001437415,0.0002362209,0.000189175,0.0001217587,0.0001725595,0.00001979555,0.0001990941,0.00007477075,0.000006293291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001330667,"about_ca_system_score_gemma":0.00003403605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001500032,"about_ca_topic_score_gemma":0.0001267491,"domain_scores_codex":[0.9982626,0.0000875888,0.0004463224,0.0005620345,0.0002610439,0.0003804492],"domain_scores_gemma":[0.9988226,0.00005552263,0.0003261369,0.0005135867,0.0002130067,0.00006909721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005776813,0.00012372,0.01865677,0.00009224849,0.0002280563,0.000002343543,0.0003189815,0.00001751547,0.9794054,0.000109989,0.0004064475,0.0005807587],"study_design_scores_gemma":[0.0009745469,0.0001000219,0.04641292,0.00009924467,0.00006500473,0.000005229315,0.0001655308,0.00002516778,0.9506593,0.0000357159,0.001128574,0.0003287698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916457,0.0007495064,0.006383198,0.00009184652,0.0001737992,0.000471441,0.0002161257,0.0000676282,0.0002007819],"genre_scores_gemma":[0.9969389,0.0007406447,0.001528311,0.00003611318,0.0002045359,0.0000321831,0.0002167823,0.00004575192,0.0002567892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02874613,"threshold_uncertainty_score":0.9632809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04189127019518431,"score_gpt":0.2884478853924926,"score_spread":0.2465566151973083,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}