{"id":"W2506519879","doi":"10.1520/mono10068m","title":"Chapter 11-Bone Morphogenetic Protein (BMP) Implants as Bone Graft Substitutes-Promises and Challenges","year":2003,"lang":"en","type":"book-chapter","venue":"","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Bone morphogenetic protein; Bone morphogenetic protein 7; Bone morphogenetic protein 2; Bone healing; Bone morphogenetic protein 5; Medicine; Bone formation; Cell biology; Matrix (chemical analysis); Regenerative medicine; Dentistry; Anatomy; Internal medicine; Chemistry; Biology; Stem cell; In vitro; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002426505,0.0005914856,0.0005313916,0.0006461069,0.0003911501,0.002238129,0.0008082234,0.001176241,0.02576474],"category_scores_gemma":[0.0002593253,0.0002918883,0.0003539886,0.0008801265,0.0004457459,0.002119376,0.0006469289,0.001979072,0.01670134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007411498,"about_ca_system_score_gemma":0.0007112382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005746405,"about_ca_topic_score_gemma":0.001777013,"domain_scores_codex":[0.9998401,0.00001705747,0.000008476469,0.00001930112,0.0001037268,0.00001131263],"domain_scores_gemma":[0.9998907,0.00004343357,0.000006516431,0.000006080461,0.00003940126,0.00001381819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005234819,0.0001689156,0.00008744611,0.001860426,0.00001235196,0.0002145968,0.0002684384,0.001139201,0.01308511,0.1011802,0.390557,0.4913739],"study_design_scores_gemma":[0.000002465369,0.00001803024,0.00005730791,0.0002508209,0.000002878092,0.0001974008,0.00003444929,0.0001394312,0.0009307587,0.006426288,0.991936,0.000004286758],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.002146721,0.4985638,0.01584778,0.008325676,0.01500265,0.0001275296,0.0002239343,0.0004205839,0.4593413],"genre_scores_gemma":[0.006526396,0.3364345,0.009544144,0.003318777,0.002949299,0.00007814854,0.0002203776,0.0002294795,0.6406989],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.02576474,"threshold_uncertainty_score":0.08619159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02509199129256375,"score_gpt":0.2270990169917863,"score_spread":0.2020070256992226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}