{"id":"W2507170775","doi":"10.1038/cr.2016.104","title":"Presenting mitochondrial antigens: PINK1, Parkin and MDVs steal the show","year":2016,"lang":"en","type":"letter","venue":"Cell Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"PINK1; Parkin; Biology; Mitochondrion; Antigen; Immune system; Cell biology; Antigen presentation; Disease; Immunology; Computational biology; Genetics; Mitophagy; Parkinson's disease; T cell; Apoptosis; Autophagy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00133235,0.000719402,0.0008220878,0.0003070907,0.001230769,0.002070402,0.0006785561,0.01504798,0.004586535],"category_scores_gemma":[0.008365868,0.0003145381,0.0006078476,0.0001855197,0.00219397,0.002805905,0.001411496,0.01664168,0.004012955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001646436,"about_ca_system_score_gemma":0.0005175575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003368208,"about_ca_topic_score_gemma":0.0005935042,"domain_scores_codex":[0.9991552,0.0002517996,0.0000808174,0.0001110705,0.0002653932,0.0001357065],"domain_scores_gemma":[0.998158,0.0009653,0.0001555655,0.0001722251,0.0002199295,0.0003290321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008247518,0.0001466226,0.001832737,0.0001676582,0.00005650746,0.02317727,0.0001738956,0.000295737,0.005014251,0.02120405,0.9030006,0.04410587],"study_design_scores_gemma":[0.0005628772,0.0003014373,0.001372541,0.0001436053,0.00005177657,0.02578398,0.0003123645,0.001323235,0.003634673,0.05653457,0.9099014,0.00007736148],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.005621209,0.007410092,0.0008160884,0.9464477,0.03231287,0.00002367037,0.00003511102,0.00009800716,0.007235288],"genre_scores_gemma":[0.1240256,0.01123789,0.001649646,0.6286287,0.1927059,0.00008072975,0.00009746254,0.0001159972,0.0414582],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01504798,"threshold_uncertainty_score":0.01534355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05543320867265565,"score_gpt":0.3229942305075738,"score_spread":0.2675610218349181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}