{"id":"W2507170775","doi":"10.1038/cr.2016.104","title":"Presenting mitochondrial antigens: PINK1, Parkin and MDVs steal the show","year":2016,"lang":"en","type":"letter","venue":"Cell Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"PINK1; Parkin; Biology; Mitochondrion; Antigen; Immune system; Cell biology; Antigen presentation; Disease; Immunology; Computational biology; Genetics; Mitophagy; Parkinson's disease; T cell; Apoptosis; Autophagy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008320088,0.0002935971,0.0002671594,0.0001443079,0.0004226376,0.0001554628,0.0006445473,0.001224718,0.0003422889],"category_scores_gemma":[0.0003515064,0.0001891299,0.0001504387,0.0001272714,0.0005917115,0.000003898379,0.0006620907,0.001761597,0.0001981234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001930854,"about_ca_system_score_gemma":0.0002214977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003160567,"about_ca_topic_score_gemma":0.00002420359,"domain_scores_codex":[0.9960563,0.001183009,0.0002926668,0.0009236329,0.0005933676,0.0009509988],"domain_scores_gemma":[0.9982101,0.0003373965,0.0001027254,0.0009561226,0.0002860022,0.0001076222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007989552,0.000007953018,0.00008411678,0.00005747548,0.00003209963,0.00006502336,0.00003246517,1.386207e-7,0.2604797,0.000008931528,0.7381262,0.001026001],"study_design_scores_gemma":[0.0005396423,0.0001922871,0.00002234325,0.00002652664,0.00001662957,0.00003910412,0.00002793984,0.000003737099,0.03407014,0.0001573457,0.9646759,0.00022841],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.04451463,0.01336883,0.001746565,0.8031698,0.01223861,0.004715137,0.0004634519,0.0001003243,0.1196826],"genre_scores_gemma":[0.01168242,0.006523748,0.0007892742,0.2162514,0.1517681,0.0006235796,0.001838065,0.0004173445,0.610106],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.5869184,"threshold_uncertainty_score":0.9446146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05543320867265565,"score_gpt":0.3229942305075738,"score_spread":0.2675610218349181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}