{"id":"W2507264934","doi":"10.1016/j.reprotox.2016.08.013","title":"Response to comments by White and colleagues","year":2016,"lang":"en","type":"letter","venue":"Reproductive Toxicology","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Hydrophobic effect; Chemistry; Guanidinium chloride; Phenol; Folding (DSP implementation); Carboxylate; Alkyl; Fluorescence; Protein folding; Fluorescence spectroscopy; Biophysics; Crystallography; Stereochemistry; Organic chemistry; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004221914,0.0003548622,0.0003950674,0.00009998147,0.00009816819,0.00002110399,0.0002879291,0.001057154,0.0000360766],"category_scores_gemma":[0.000509106,0.0002971333,0.00007046293,0.00007638949,0.0002439872,0.000003111576,0.0004133568,0.000410171,0.0000286049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006258064,"about_ca_system_score_gemma":0.00009937937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004829235,"about_ca_topic_score_gemma":0.00000499529,"domain_scores_codex":[0.9972998,0.0004657308,0.0002475207,0.001376134,0.0001384812,0.0004723051],"domain_scores_gemma":[0.9985895,0.00005266951,0.0001500338,0.000983619,0.0001357285,0.0000884469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006497368,0.000008694426,0.0001326868,0.00001004363,0.00008581991,0.00002292897,0.00002576234,2.423945e-7,0.3196944,0.000003033418,0.6784692,0.0008974781],"study_design_scores_gemma":[0.0004031811,0.000953418,0.0003004709,0.00001506175,0.00002469606,0.00008681024,0.000006984347,1.795391e-7,0.04466454,0.0002599792,0.9529207,0.0003639518],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.06791896,0.001155489,0.0006223422,0.9272709,0.000667265,0.0009058053,0.0006778655,0.00002719298,0.0007541479],"genre_scores_gemma":[0.009671499,0.0002217557,0.001341696,0.9110677,0.006361753,0.0002412267,0.000716672,0.0001313566,0.07024629],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.2750299,"threshold_uncertainty_score":0.9999481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007058994209941604,"score_gpt":0.2526159010192923,"score_spread":0.2455569068093507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}