{"id":"W2507264934","doi":"10.1016/j.reprotox.2016.08.013","title":"Response to comments by White and colleagues","year":2016,"lang":"en","type":"letter","venue":"Reproductive Toxicology","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Hydrophobic effect; Chemistry; Guanidinium chloride; Phenol; Folding (DSP implementation); Carboxylate; Alkyl; Fluorescence; Protein folding; Fluorescence spectroscopy; Biophysics; Crystallography; Stereochemistry; Organic chemistry; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005421896,0.001408097,0.001977139,0.00090123,0.006365763,0.005672414,0.00296679,0.07605812,0.009349038],"category_scores_gemma":[0.03811182,0.001328126,0.001795337,0.000669412,0.003560169,0.003263678,0.003377051,0.05516048,0.01018425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005730051,"about_ca_system_score_gemma":0.004705225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005718159,"about_ca_topic_score_gemma":0.009063547,"domain_scores_codex":[0.9954326,0.0007888578,0.0005114078,0.0007004424,0.001523531,0.001043078],"domain_scores_gemma":[0.9896737,0.004764346,0.0009929579,0.0003276162,0.002050361,0.002191032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003540399,0.00001385522,0.0002114401,0.00002591941,0.00001131227,0.00119869,0.0001160696,0.00003018011,0.0001146835,0.0006662458,0.9952115,0.002364768],"study_design_scores_gemma":[0.0001362469,0.00008322918,0.001482777,0.0003835173,0.00005934523,0.002154171,0.0008288937,0.000442985,0.000514253,0.005201529,0.9886144,0.00009862459],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002152283,0.0006822886,0.00008239533,0.9558337,0.04162251,0.00001716141,0.00004458361,0.00002871537,0.001473355],"genre_scores_gemma":[0.001754495,0.0005320355,0.0001194182,0.9587474,0.02952186,0.00004577324,0.0000266033,0.00002908981,0.009223094],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.07605812,"threshold_uncertainty_score":0.0415746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007058994209941604,"score_gpt":0.2526159010192923,"score_spread":0.2455569068093507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}