{"id":"W2507306980","doi":"10.1038/nmeth.3995","title":"A proposal for validation of antibodies","year":2016,"lang":"en","type":"article","venue":"Nature Methods","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":645,"is_retracted":false,"has_abstract":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"National Institute on Drug Abuse","keywords":"Antibody; Computer science; Computational biology; Medicine; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.07534462,0.003361606,0.002686521,0.005658481,0.004141671,0.009992179,0.01004872,0.01184231,0.006085177],"category_scores_gemma":[0.07949501,0.002663695,0.003839728,0.002498034,0.01504869,0.01051426,0.008679961,0.0103853,0.005111277],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002794789,"about_ca_system_score_gemma":0.005429376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001349885,"about_ca_topic_score_gemma":0.0008031007,"domain_scores_codex":[0.9546481,0.02208153,0.00354881,0.007541836,0.009382418,0.002797211],"domain_scores_gemma":[0.9323745,0.02161187,0.002791157,0.02189928,0.01893609,0.002387061],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001330813,0.001008149,0.01079227,0.002171851,0.0004264544,0.0008963721,0.00230658,0.001785393,0.2576198,0.5400236,0.02308583,0.1585529],"study_design_scores_gemma":[0.0005717516,0.003215451,0.005262482,0.001941272,0.0006383973,0.003121589,0.001124148,0.00908357,0.3033361,0.2875239,0.3838071,0.0003743418],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.02767581,0.00730639,0.9143656,0.01799526,0.004122591,0.001579773,0.0005930414,0.001571609,0.02478981],"genre_scores_gemma":[0.1337149,0.0032692,0.8306345,0.0127371,0.001225248,0.003538002,0.001626682,0.0006199032,0.01263446],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.9246554,"threshold_uncertainty_score":0.3984652,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04220168583204635,"score_gpt":0.4691830622997801,"score_spread":0.4269813764677337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}