{"id":"W2507431544","doi":"10.1021/acsinfecdis.6b00095","title":"Structure–Function Profile of MmpL3, the Essential Mycolic Acid Transporter from <i>Mycobacterium tuberculosis</i>","year":2016,"lang":"en","type":"article","venue":"ACS Infectious Diseases","topic":"Mycobacterium research and diagnosis","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Fonds de Recherche du Québec - Santé; Potts Memorial Foundation","keywords":"Mycolic acid; Corynebacterium glutamicum; Biology; Biochemistry; Transmembrane protein; Membrane topology; Biogenesis; Transmembrane domain; Mycobacterium tuberculosis; Mycobacterium; Cell biology; Genetics; Amino acid; Bacteria; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001009348,0.0001924096,0.0001308468,0.000107017,0.000123002,0.0001615598,0.0002246112,0.0002861592,0.0006204332],"category_scores_gemma":[0.0001558667,0.00006101775,0.0002377563,0.0001825456,0.0001099296,0.0001345628,0.00006096267,0.0002640704,0.0002363351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004730372,"about_ca_system_score_gemma":0.0001636352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003118954,"about_ca_topic_score_gemma":0.001780115,"domain_scores_codex":[0.9999467,0.000007087623,0.000003005531,0.000011664,0.00001918133,0.00001238161],"domain_scores_gemma":[0.9999161,0.00001309857,0.00002537427,0.000004909546,0.00002012228,0.00002033755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007430182,0.00006554827,0.003674913,0.00007415164,0.00001116329,0.0002605711,0.00004298244,0.0008605693,0.9907006,0.0001468803,0.0002375513,0.003182015],"study_design_scores_gemma":[0.00007521991,0.001085452,0.08363149,0.00002130044,0.00006225516,0.001720033,0.0001337311,0.02857183,0.8759783,0.0001564538,0.00853298,0.00003103437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978027,0.0008207805,0.0003615897,0.00005395095,0.000003596581,0.000005979431,0.0005183993,0.00001718132,0.0004158767],"genre_scores_gemma":[0.9951212,0.0004806493,0.0009005564,0.00003763264,0.000004068499,0.000005412822,0.002670825,0.000007928543,0.0007717782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003118954,"threshold_uncertainty_score":0.006201625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006070366138056308,"score_gpt":0.2382975434883227,"score_spread":0.2322271773502664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}