{"id":"W2507878657","doi":"10.1371/journal.ppat.1005821","title":"Francisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins and Harbors a Unique N-terminal Extension Required for Virulence","year":2016,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"Direction Générale de l’Armement; University of California, Los Angeles; Umeå Centre for Microbial Research; Université de Lyon; Fondation Innovations en Infectiologie; Fondation pour la Recherche Médicale; University of Washington; University of Wollongong; Laboratoire d'Excellence Ecofect; Agence Nationale de la Recherche","keywords":"Francisella tularensis; Francisella; Virulence; Tularemia; Type VI secretion system; Biology; Pathogenicity island; Secretion; Genetics; Microbiology; Cell biology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006027478,0.0002709673,0.0002294006,0.0002704278,0.0001409137,0.0002223803,0.0001141356,0.0002347333,0.0002446213],"category_scores_gemma":[0.0001038317,0.0000653887,0.0002124117,0.0002224166,0.0001071911,0.0001610908,0.0001283792,0.0001428675,0.0001769974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001539788,"about_ca_system_score_gemma":0.0001165432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004730449,"about_ca_topic_score_gemma":0.0005201438,"domain_scores_codex":[0.9999568,0.000004896849,0.000003816668,0.00001022828,0.00001286438,0.00001135653],"domain_scores_gemma":[0.9999449,0.000005593836,0.00001959813,0.000004543578,0.00001156132,0.0000138032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007061191,0.0000227316,0.003644536,0.00003252973,0.00000745958,0.0002560221,0.0000408398,0.00008820885,0.99188,0.00006630807,0.00004108117,0.003849691],"study_design_scores_gemma":[0.00002901465,0.001026935,0.1198135,0.00003525839,0.0001075067,0.008259206,0.0003438234,0.007497504,0.8474504,0.000355274,0.01504207,0.00003946418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946759,0.0007320376,0.004028189,0.00003267364,0.000005468207,0.00001074983,0.0001854551,0.00005224834,0.0002773916],"genre_scores_gemma":[0.9916858,0.0004745804,0.005592785,0.00003564265,0.00001316208,0.0000194104,0.00155976,0.000008819237,0.0006100608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004730449,"threshold_uncertainty_score":0.00111717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02739550395328797,"score_gpt":0.2617946136932834,"score_spread":0.2343991097399955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}