{"id":"W2507878657","doi":"10.1371/journal.ppat.1005821","title":"Francisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins and Harbors a Unique N-terminal Extension Required for Virulence","year":2016,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"Direction Générale de l’Armement; University of California, Los Angeles; Umeå Centre for Microbial Research; Université de Lyon; Fondation Innovations en Infectiologie; Fondation pour la Recherche Médicale; University of Washington; University of Wollongong; Laboratoire d'Excellence Ecofect; Agence Nationale de la Recherche","keywords":"Francisella tularensis; Francisella; Virulence; Tularemia; Type VI secretion system; Biology; Pathogenicity island; Secretion; Genetics; Microbiology; Cell biology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003144397,0.0002268937,0.0003208146,0.00007961165,0.0001000862,0.00001976957,0.0002096054,0.0002190489,0.00001153213],"category_scores_gemma":[0.0003915289,0.0001704704,0.0001168529,0.000128063,0.0001508978,0.000008518228,0.0001890489,0.00005475195,0.000007533202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001811043,"about_ca_system_score_gemma":0.0001264599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002696077,"about_ca_topic_score_gemma":0.00003015055,"domain_scores_codex":[0.9983222,0.00005047697,0.0003240794,0.0006228186,0.0002396735,0.0004406826],"domain_scores_gemma":[0.9986701,0.00004408009,0.0001026072,0.0004992525,0.0004436817,0.0002403057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006862386,0.0001547618,0.0003089054,0.00009498974,0.00003882858,0.000009186778,0.00008046872,4.843304e-7,0.9855512,0.00003873361,0.0001131668,0.012923],"study_design_scores_gemma":[0.001449623,0.001183358,0.005459236,0.0001929269,0.00003648896,0.00001566475,0.00002247464,0.00006665144,0.9853243,0.00006732754,0.00586759,0.0003143282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9703298,0.000245049,0.02721542,0.0002103383,0.00008564981,0.001126102,0.0007347012,0.00001395041,0.00003897946],"genre_scores_gemma":[0.9896302,0.0002732921,0.009189444,0.0002248602,0.0001495493,0.0002345372,0.00002957484,0.00004749571,0.0002210827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01930036,"threshold_uncertainty_score":0.6951582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02739550395328797,"score_gpt":0.2617946136932834,"score_spread":0.2343991097399955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}