{"id":"W2508311538","doi":"10.1016/j.freeradbiomed.2015.10.269","title":"Bisphenol A Induces DNA Double Strand Break and Activates the ATM-P53-GDF15 Signaling Pathway Leading to Cell Cycle Arrest and Senescence in Human Fetal Lung Fibroblasts (HFLF)","year":2015,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University; Health Canada","funders":"","keywords":"Ovalbumin; Allergy; Immunology; Food allergy; Eosinophil; Splenocyte; Immunoglobulin E; Offspring; Bronchoalveolar lavage; Allergen; Anaphylaxis; Medicine; Lung; Internal medicine; Biology; Antibody; Asthma; Pregnancy; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002296945,0.0004118467,0.0001831052,0.000558037,0.0002564674,0.0002270196,0.000236435,0.0003633517,0.00289023],"category_scores_gemma":[0.000133987,0.0002332141,0.0005623174,0.0003052185,0.0001733586,0.000249844,0.0002270475,0.0004903033,0.0005366957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003326059,"about_ca_system_score_gemma":0.0002693168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003259971,"about_ca_topic_score_gemma":0.002874508,"domain_scores_codex":[0.9998041,0.00003764628,0.00002371859,0.00003393703,0.00004362424,0.00005701075],"domain_scores_gemma":[0.9998627,0.00003696398,0.00002742344,0.00002717896,0.00001835469,0.00002739276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003146926,0.0000679715,0.0003187312,0.00002783865,0.00001104158,0.000101883,0.00003019821,0.00004130535,0.9979129,0.0001031835,0.00006090399,0.001009335],"study_design_scores_gemma":[0.000025111,0.0003970698,0.006751127,0.000004989879,0.00001645671,0.0001883474,0.00005615104,0.0004445394,0.9902316,0.00006102099,0.001818707,0.000004899297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951352,0.001023939,0.00169976,0.0001185433,0.00005580892,0.0000333434,0.0005900213,0.0000573711,0.001286088],"genre_scores_gemma":[0.9926301,0.00095444,0.001420797,0.00008371442,0.00001276869,0.00004711699,0.001255697,0.00001115975,0.003584171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003259971,"threshold_uncertainty_score":0.009668767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01540132423589927,"score_gpt":0.3229779009177269,"score_spread":0.3075765766818276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}