{"id":"W2508618197","doi":"10.1016/j.gene.2016.09.013","title":"Disruption of the UBF gene induces aberrant somatic nucleolar bodies and disrupts embryo nucleolar precursor bodies","year":2016,"lang":"en","type":"article","venue":"Gene","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Nucleolus; Biology; Ribosome biogenesis; Transcription (linguistics); Gene; Cell biology; Somatic cell; Nucleolus organizer region; Heterochromatin; Molecular biology; Genetics; RNA; Chromosome; Ribosome; Nucleus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001491302,0.0001884953,0.000195864,0.00002688933,0.0001386738,0.00002509241,0.0002428356,0.0001357796,0.00001294942],"category_scores_gemma":[0.00006500201,0.0001138957,0.0001011365,0.00002541949,0.0001946795,0.000008134672,0.000271047,0.00005047525,0.000007132802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001447587,"about_ca_system_score_gemma":0.00003687678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001152262,"about_ca_topic_score_gemma":0.00007849755,"domain_scores_codex":[0.9989905,0.0000592405,0.000278101,0.0002991698,0.0001369516,0.0002360077],"domain_scores_gemma":[0.9992117,0.00001530043,0.0001811354,0.0004678042,0.00006413199,0.00005998101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002175676,0.00004142074,0.00408486,0.00004855195,0.000075497,6.965011e-7,0.0003577336,0.000008402772,0.9910346,0.00004646805,0.0001273844,0.004152575],"study_design_scores_gemma":[0.0006581071,0.000171218,0.09225103,0.00006834221,0.00007014877,0.00003138477,0.0001674193,0.000136553,0.9038397,0.001003457,0.001334124,0.000268492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965611,0.002073522,0.000245603,0.0003643674,0.0001983499,0.0002122433,0.00009573189,0.00001047747,0.0002386332],"genre_scores_gemma":[0.9966274,0.001339654,0.0011187,0.00006875518,0.0001136807,0.00001611115,0.00001984969,0.00002869495,0.0006671298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08816617,"threshold_uncertainty_score":0.4644533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007721494546086114,"score_gpt":0.2182067817963237,"score_spread":0.2104852872502376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}