{"id":"W2508919572","doi":"10.1200/jco.2013.31.15_suppl.2007","title":"Temozolomide chemotherapy versus radiotherapy in molecularly characterized (1p loss) low-grade glioma: A randomized phase III intergroup study by the EORTC/NCIC-CTG/TROG/MRC-CTU (EORTC 22033-26033).","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Temozolomide; Medicine; Internal medicine; Clinical endpoint; Oncology; Radiation therapy; Chemotherapy; Glioma; Progression-free survival; Chemoradiotherapy; Phases of clinical research; Randomized controlled trial; Chemotherapy regimen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002188143,0.001227887,0.002150321,0.000544645,0.0002755454,0.0008026543,0.0008331914,0.001086294,0.003983388],"category_scores_gemma":[0.001485176,0.0004359336,0.001210406,0.0005699834,0.0009093848,0.0006164649,0.0003368816,0.002090617,0.0005538859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009910242,"about_ca_system_score_gemma":0.00113431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001230163,"about_ca_topic_score_gemma":0.00305308,"domain_scores_codex":[0.9993217,0.0004730278,0.0000284827,0.00006975204,0.00003841365,0.00006867548],"domain_scores_gemma":[0.9991025,0.0002805383,0.0002465989,0.00006407794,0.00003846068,0.0002679592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.967813,0.01209543,0.0009857286,0.0003725288,0.0006670575,0.00002566785,0.00005486618,0.0004136634,0.003056126,0.00008739458,0.0006371032,0.01379144],"study_design_scores_gemma":[0.8579688,0.1362355,0.003228992,0.00002925359,0.0005591215,0.00003668945,0.00002586586,0.000505235,0.0006015802,0.0001229479,0.0006725367,0.00001346017],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993357,0.002296884,0.0003864356,0.0003461223,0.0002223784,0.002068612,0.0006046557,0.00004149933,0.0006764551],"genre_scores_gemma":[0.9876302,0.003186873,0.00132914,0.0008453159,0.0003434367,0.003531111,0.0009868519,0.00002779184,0.002119369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003983388,"threshold_uncertainty_score":0.01332575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04644971527527979,"score_gpt":0.4261073248753325,"score_spread":0.3796576096000527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}