{"id":"W2509053325","doi":"10.1182/blood.v122.21.2680.2680","title":"Chemosensitization and Mobilization Of AML/ALL/MDS With Plerixafor (AMD 3100), a CXCR4 Antagonist: A Phase I Study Of Plerixafor + Cytarabine and Etoposide In Pediatric Patients With Acute Leukemia and MDS","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital","funders":"","keywords":"Plerixafor; Medicine; Cytarabine; Etoposide; CXCR4 antagonist; Leukemia; Bone marrow; CXCR4; Acute leukemia; Chemotherapy; Internal medicine; Pharmacology; Oncology; Inflammation; Chemokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001436105,0.001438933,0.002209745,0.0006262115,0.000476813,0.0007813176,0.001253951,0.0008309709,0.00193495],"category_scores_gemma":[0.0005519578,0.000622985,0.00129564,0.00057051,0.00129679,0.0008232783,0.0004785002,0.002606002,0.0005303609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001038094,"about_ca_system_score_gemma":0.002406344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001390494,"about_ca_topic_score_gemma":0.003225304,"domain_scores_codex":[0.9995189,0.0002235422,0.00003485681,0.00006829425,0.00004107943,0.0001132332],"domain_scores_gemma":[0.9993117,0.0000918576,0.0001244577,0.00005346206,0.00003388291,0.0003847081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.508101,0.2057087,0.01534805,0.001833522,0.001634761,0.0009872114,0.0009708171,0.00459406,0.1041323,0.0006795324,0.003292436,0.1527175],"study_design_scores_gemma":[0.2134238,0.7616886,0.01185769,0.00005004048,0.0004938981,0.0005214318,0.0001207001,0.0007657026,0.008497735,0.0001521072,0.002400564,0.00002768528],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939665,0.001579378,0.0004007285,0.0001993467,0.00005073106,0.002552561,0.0004476524,0.00006083259,0.0007423708],"genre_scores_gemma":[0.9900672,0.001978413,0.002048855,0.0003976542,0.0001955946,0.00335398,0.0008239028,0.00001957909,0.001114862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002209745,"threshold_uncertainty_score":0.007594883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007548646088943208,"score_gpt":0.2571508213574301,"score_spread":0.2496021752684869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}