{"id":"W2509195760","doi":"10.1039/c6ra21389h","title":"Supramolecular peptide amphiphile based nanocarrier for pH-triggered Dox release, overcoming drug resistance","year":2016,"lang":"en","type":"article","venue":"RSC Advances","topic":"Supramolecular Self-Assembly in Materials","field":"Materials Science","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Regional Municipality of Waterloo; University of Waterloo","funders":"","keywords":"Nanocarriers; Amphiphile; Supramolecular chemistry; Peptide; Drug; Chemistry; Doxorubicin; Conjugate; Biophysics; Drug delivery; Combinatorial chemistry; Copolymer; Nanotechnology; Materials science; Pharmacology; Biochemistry; Organic chemistry; Polymer; Medicine; Molecule; Biology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001195825,0.0002108225,0.0001783374,0.0001321319,0.000102086,0.0001506547,0.0001467126,0.0002589691,0.0008415463],"category_scores_gemma":[0.0001156098,0.0001024723,0.0001201472,0.0000780971,0.0001057376,0.0001804472,0.0001691989,0.0003618187,0.0002487696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002560323,"about_ca_system_score_gemma":0.0001529177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003243517,"about_ca_topic_score_gemma":0.0007002398,"domain_scores_codex":[0.9999423,0.000007731623,0.000005461063,0.00001585268,0.00001340581,0.00001524916],"domain_scores_gemma":[0.9999564,0.000007239335,0.000009954115,0.000004396687,0.000006252116,0.00001582172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003866153,0.00002098414,0.00002130921,0.00002244174,0.000002873003,0.00002391626,0.000008779349,0.000101516,0.9980108,0.00008813858,0.00005499315,0.001605658],"study_design_scores_gemma":[0.00001491431,0.0001073904,0.0002852098,0.000001415925,0.0000061032,0.0000476918,0.000003356054,0.001176683,0.997152,0.00001635712,0.001185219,0.000003752438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827827,0.001962654,0.01235825,0.0002025123,0.00005797405,0.00007628085,0.0001518087,0.0002576763,0.00215022],"genre_scores_gemma":[0.9925846,0.0003698712,0.004400769,0.00005793466,0.000005907329,0.00003478104,0.00007851869,0.00001714155,0.002450389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008415463,"threshold_uncertainty_score":0.002815306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009246207489270995,"score_gpt":0.2533089822569272,"score_spread":0.2440627747676562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}