{"id":"W2509283375","doi":"10.1038/srep32759","title":"Loss of mesenchymal bone morphogenetic protein signaling leads to development of reactive stroma and initiation of the gastric neoplastic cascade","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Sherbrooke","keywords":"Bone morphogenetic protein; Stroma; Bone morphogenetic protein 2; Mesenchymal stem cell; Cell biology; Cascade; Bone morphogenetic protein 6; Biology; Bone morphogenetic protein 7; Cancer research; Chemistry; Computational biology; Genetics; Immunology; Gene; In vitro; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007206874,0.0000818653,0.0001499613,0.0000813043,0.00007888045,0.000005768473,0.00006223506,0.00007206105,0.000004305154],"category_scores_gemma":[0.0002327956,0.00004849392,0.00003845101,0.0002096805,0.0001850173,0.000004195991,0.00007933354,0.00003254611,5.638942e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001953096,"about_ca_system_score_gemma":0.0003920021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009111582,"about_ca_topic_score_gemma":0.00001143964,"domain_scores_codex":[0.9987163,0.00006952882,0.0005135044,0.0003018239,0.0002544783,0.0001443621],"domain_scores_gemma":[0.9989166,0.00001509241,0.0005014049,0.0002706939,0.0002355367,0.00006070381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002189508,0.00003016954,0.0158382,0.00006768324,0.00001670463,0.00000551745,0.0002355063,0.00003787105,0.9831743,0.000008557449,0.00002487249,0.0005387259],"study_design_scores_gemma":[0.0001261635,0.0001079722,0.02937112,0.0002744567,0.00001141769,0.00009119369,0.0000649226,0.000001429181,0.9696858,0.00005403402,0.000154428,0.00005705171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997833,0.0001525966,0.001137415,0.00002909852,0.0003307624,0.0003975728,0.000006419564,0.000001854775,0.0001112685],"genre_scores_gemma":[0.9988499,0.000001885586,0.0007356839,0.000002144709,0.00001428065,0.00001250071,0.000005987973,0.000006497566,0.0003711468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01353292,"threshold_uncertainty_score":0.1977525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019611527546554,"score_gpt":0.2371681420409286,"score_spread":0.2269720267654631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}