{"id":"W2509283375","doi":"10.1038/srep32759","title":"Loss of mesenchymal bone morphogenetic protein signaling leads to development of reactive stroma and initiation of the gastric neoplastic cascade","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Sherbrooke","keywords":"Bone morphogenetic protein; Stroma; Bone morphogenetic protein 2; Mesenchymal stem cell; Cell biology; Cascade; Bone morphogenetic protein 6; Biology; Bone morphogenetic protein 7; Cancer research; Chemistry; Computational biology; Genetics; Immunology; Gene; In vitro; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001126196,0.0003492639,0.0001955037,0.0003584466,0.0001048782,0.0002161634,0.0001656839,0.0002987771,0.0011765],"category_scores_gemma":[0.0001039814,0.0002891791,0.0002738261,0.0001159337,0.0002865845,0.0001575104,0.0003271205,0.000629512,0.0003271917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002011882,"about_ca_system_score_gemma":0.0001699789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003220086,"about_ca_topic_score_gemma":0.0003828733,"domain_scores_codex":[0.9998288,0.00002691326,0.00001681026,0.0000327231,0.00005386495,0.00004083169],"domain_scores_gemma":[0.9998448,0.000020598,0.00004832923,0.00001717494,0.000007097695,0.00006204424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009469214,0.00001937329,0.0002151808,0.00001225123,0.000002952653,0.0001324563,0.000007095174,0.00003650606,0.9988683,0.0001284774,0.00001136946,0.0004713489],"study_design_scores_gemma":[0.0000217564,0.0004263884,0.005912338,0.000005974154,0.00001666348,0.001159639,0.00002606478,0.0007699268,0.9900936,0.0001061653,0.001457479,0.000003983924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960523,0.0005752211,0.002150569,0.00005579699,0.00001254892,0.00002512134,0.000177349,0.00007627076,0.0008749032],"genre_scores_gemma":[0.9952022,0.0005802341,0.001538916,0.00003371533,0.000005377164,0.00003191963,0.0002463101,0.00001888773,0.002342468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0011765,"threshold_uncertainty_score":0.003935814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019611527546554,"score_gpt":0.2371681420409286,"score_spread":0.2269720267654631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}