{"id":"W2509320806","doi":"10.1016/j.virusres.2016.08.008","title":"Alfalfa dwarf cytorhabdovirus P protein is a local and systemic RNA silencing supressor which inhibits programmed RISC activity and prevents transitive amplification of RNA silencing","year":2016,"lang":"en","type":"article","venue":"Virus Research","topic":"Plant Virus Research Studies","field":"Agricultural and Biological Sciences","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Agriculture and Agri-Food Canada; Australian Research Council; University of Queensland; Queensland University of Technology; Department of Agriculture, Fisheries and Forestry, Australian Government","keywords":"Biology; Gene silencing; RNA-induced silencing complex; Trans-acting siRNA; RNA silencing; Small interfering RNA; Argonaute; RNA-induced transcriptional silencing; RNA; RNA interference; Cell biology; RNA-binding protein; Molecular biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001202541,0.0003446625,0.0001809139,0.0001834827,0.0002206743,0.0002668745,0.0002452079,0.0002906107,0.0006532714],"category_scores_gemma":[0.0001196282,0.0001337907,0.0002159099,0.00009234167,0.0003463515,0.0001699912,0.0001467851,0.0004888705,0.0003275699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005546602,"about_ca_system_score_gemma":0.0003003425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009735827,"about_ca_topic_score_gemma":0.001407818,"domain_scores_codex":[0.9999099,0.00001394811,0.000007172383,0.0000267826,0.00002217448,0.00002009435],"domain_scores_gemma":[0.9998744,0.0000262649,0.00003378934,0.00001736012,0.000009513077,0.0000387672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001018718,0.00001085061,0.00009808718,0.00001014128,0.000002174781,0.00005107156,0.000005006223,0.00003038999,0.9989673,0.00009199678,0.00002789897,0.0006032764],"study_design_scores_gemma":[0.00001913241,0.0001983334,0.00192055,0.000001450381,0.000009397972,0.0002509847,0.0000128976,0.0006587394,0.9956469,0.0000499721,0.001228125,0.000003536724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934634,0.0007660499,0.004038286,0.0001038047,0.00002366745,0.00001733373,0.0001826676,0.0001356978,0.001269043],"genre_scores_gemma":[0.9952323,0.0002180899,0.001705874,0.00003938354,0.00001137555,0.00001126763,0.000431544,0.00003008072,0.002320017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009735827,"threshold_uncertainty_score":0.004024386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06888453415817956,"score_gpt":0.3156563219484974,"score_spread":0.2467717877903178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}