{"id":"W2509351424","doi":"10.1016/j.stemcr.2016.06.012","title":"G9a and ZNF644 Physically Associate to Suppress Progenitor Gene Expression during Neurogenesis","year":2016,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Neurogenesis; Gene silencing; Histone methyltransferase; Cell biology; Cellular differentiation; Progenitor cell; Cell fate determination; Regulation of gene expression; Histone; Regulator; Zebrafish; DNA methylation; Gene expression; Genetics; Gene; Stem cell; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001506297,0.0001546194,0.0001436653,0.00003116366,0.00009220716,0.00002860425,0.00006856927,0.0001112625,0.000005216727],"category_scores_gemma":[0.00002870962,0.0001167153,0.00006896132,0.00004889626,0.00002079939,0.000005057647,0.0001711804,0.00002872781,0.000004706993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001403541,"about_ca_system_score_gemma":0.0000299107,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003770928,"about_ca_topic_score_gemma":0.000002543258,"domain_scores_codex":[0.998726,0.00005961498,0.0002720364,0.0005166678,0.000181825,0.0002439049],"domain_scores_gemma":[0.9991674,0.00001268357,0.0001686097,0.0003967523,0.00009098172,0.0001635249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002510675,0.00003321355,0.01887296,0.00001746115,0.000011653,0.0000414472,0.00002688309,0.000009649331,0.9780363,3.249502e-7,0.00005688411,0.002868123],"study_design_scores_gemma":[0.0001943417,0.00009869034,0.01673915,0.00001770896,0.00001461806,0.00001337282,0.000007029731,9.133714e-7,0.9790996,0.00001946692,0.00362241,0.0001726814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998046,0.0006644447,0.0004421567,0.00005637637,0.0002003382,0.0002521338,0.00001022134,0.00001832057,0.0003099908],"genre_scores_gemma":[0.9968745,0.000141795,0.00046609,0.00002142527,0.000254731,0.00003975376,0.00001110084,0.0000338862,0.002156715],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003565526,"threshold_uncertainty_score":0.4759512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005986180402613558,"score_gpt":0.2160686967908803,"score_spread":0.2100825163882667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}