{"id":"W2509369257","doi":"10.1371/journal.pone.0161587","title":"The O-Antigen Flippase Wzk Can Substitute for MurJ in Peptidoglycan Synthesis in Helicobacter pylori and Escherichia coli","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Flippase; Lipid II; Peptidoglycan; Biology; Cell envelope; Bacillus subtilis; Escherichia coli; Biogenesis; Biochemistry; ATP-binding cassette transporter; Lipid bilayer; Inner membrane; Bacterial outer membrane; Cell biology; Microbiology; Cell wall; Bacteria; Transporter; Phosphatidylserine; Genetics; Phospholipid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000184564,0.0001397008,0.0001805711,0.00004627618,0.00006048773,0.00002555092,0.0001887652,0.0002298534,0.000006509716],"category_scores_gemma":[0.0002108273,0.00009174765,0.00003387986,0.00007787113,0.0001506344,0.000002585083,0.0001068197,0.00006339097,0.000002742169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001973788,"about_ca_system_score_gemma":0.00005253198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000775706,"about_ca_topic_score_gemma":0.003159854,"domain_scores_codex":[0.9990477,0.00003801494,0.0002059136,0.000317377,0.00006699106,0.0003240013],"domain_scores_gemma":[0.9994944,0.00004968794,0.00005778864,0.0003000285,0.00004298514,0.00005505497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001716183,0.0001188072,0.009942356,0.0000154064,0.00005689666,0.000001676122,0.00001764253,1.094215e-7,0.9853899,0.00009022544,0.00003625767,0.004159035],"study_design_scores_gemma":[0.0006472496,0.0001741763,0.02604506,0.00006305114,0.00002025225,8.784685e-7,0.00002016866,0.00001191081,0.9651588,0.0001080349,0.007576046,0.0001744353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996074,0.0003221419,0.0000187199,0.003038706,0.00005645148,0.0003695721,0.0000681845,0.000008408395,0.00004378658],"genre_scores_gemma":[0.9961368,0.002417739,0.0007050386,0.0001161068,0.0001468444,0.0001743398,0.00001164675,0.00002092337,0.0002705707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02023123,"threshold_uncertainty_score":0.3741361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01927323290063333,"score_gpt":0.2096986096396253,"score_spread":0.190425376738992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}