{"id":"W2509409746","doi":"10.1111/bph.13559","title":"Structural commonality of C1q TNF‐related proteins and their potential to activate relaxin/insulin‐like family peptide receptor 1 signalling pathways in cancer cells","year":2016,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Pregnancy-related medical research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Manitoba Health; University of Manitoba","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Natural Sciences and Engineering Research Council of Canada","keywords":"Relaxin; Receptor; Signal transduction; Insulin; Signalling; Insulin receptor; Cell biology; Biology; Signalling pathways; Cancer research; Chemistry; Endocrinology; Biochemistry; Insulin resistance","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001883912,0.0005079019,0.00322342,0.000588902,0.00009033074,0.00002573939,0.0005893121,0.0008430221,0.001022745],"category_scores_gemma":[0.0004278653,0.0003935173,0.0005932232,0.0005556014,0.0004179081,0.0001692659,0.0003175415,0.003798276,0.00001531202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007158428,"about_ca_system_score_gemma":0.002250036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002821635,"about_ca_topic_score_gemma":0.00002175969,"domain_scores_codex":[0.9941481,0.001381468,0.002348396,0.0005359764,0.0007626262,0.0008234733],"domain_scores_gemma":[0.9962521,0.0007218886,0.001446654,0.0001532468,0.0006273917,0.0007987103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0005580566,0.0002054702,0.00000479299,0.004950023,0.001023441,0.002075238,0.0001345393,0.000008868062,0.1128026,0.00000272551,0.002009126,0.8762251],"study_design_scores_gemma":[0.02114328,0.003471279,0.0005429871,0.5887443,0.002971383,0.01085004,0.0001500204,0.0001126677,0.02254713,0.0004322143,0.3474624,0.001572252],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06442373,0.9313689,0.00005875456,0.0003771056,0.001261872,0.00201388,0.0004151177,0.00001829237,0.00006229686],"genre_scores_gemma":[0.02085606,0.9777203,0.0002898445,0.000222718,0.0005509553,0.00008563183,0.00002231748,0.00009492696,0.0001571962],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8746529,"threshold_uncertainty_score":0.9998904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05509269118291622,"score_gpt":0.3646423102574636,"score_spread":0.3095496190745474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}