{"id":"W2509507246","doi":"10.1016/j.molmet.2016.08.010","title":"The regulator of G-protein signaling RGS16 promotes insulin secretion and β-cell proliferation in rodent and human islets","year":2016,"lang":"en","type":"article","venue":"Molecular Metabolism","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Regulator; Cell biology; Rodent; Islet; Secretion; Biology; Signal transduction; Cell growth; Insulin; Internal medicine; Endocrinology; Gene; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003736932,0.0001005597,0.0002074862,0.00008437887,0.00006025345,0.00001823522,0.00002892762,0.00005350175,0.00001324557],"category_scores_gemma":[0.0001982639,0.00005767102,0.00002906328,0.00009258657,0.00008422966,0.00005318499,0.00002531272,0.00006030694,0.000001549478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001189998,"about_ca_system_score_gemma":0.00002720797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002982478,"about_ca_topic_score_gemma":0.000002398085,"domain_scores_codex":[0.9991606,0.0001024404,0.0002428357,0.000181373,0.0001834955,0.0001292698],"domain_scores_gemma":[0.9995784,0.0000350369,0.00008817576,0.00016696,0.00006893102,0.00006251578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005246579,0.00003940341,0.002097319,0.00004771912,0.00001412067,0.000003127624,0.0001316471,4.027825e-7,0.9902655,0.003523186,0.000004301393,0.003820747],"study_design_scores_gemma":[0.002104614,0.00008557659,0.02885135,0.0001558129,0.00005398297,0.000004077874,0.00003998373,0.0001016619,0.965799,0.002081759,0.0006455634,0.00007661548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993246,0.004696303,0.0005638605,0.000737745,0.00002955887,0.0005146106,0.000001984268,0.00001525759,0.0001946966],"genre_scores_gemma":[0.998974,0.00006558962,0.0004861263,0.00008632687,0.00003884118,0.00004255882,0.000003864649,0.00001239033,0.0002902748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02675403,"threshold_uncertainty_score":0.2351756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007071515002187169,"score_gpt":0.2217640567050371,"score_spread":0.21469254170285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}