{"id":"W2509656165","doi":"10.1080/2162402x.2016.1224044","title":"Impaired functional responses in follicular lymphoma CD8+TIM-3+T lymphocytes following TCR engagement","year":2016,"lang":"en","type":"article","venue":"OncoImmunology","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Institute of Cancer Research; Institut National Du Cancer; Agence Nationale de la Recherche","keywords":"Cytotoxic T cell; Ex vivo; CD8; Immunology; Granzyme B; Biology; Immune system; Interleukin 21; Cancer research; In vivo; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001551131,0.0002929907,0.0001898021,0.000186678,0.0001105995,0.0002627992,0.000116761,0.0002825985,0.001262185],"category_scores_gemma":[0.0001519278,0.00009042065,0.0001560874,0.00009341527,0.0001587045,0.0002035632,0.0001696005,0.0003518927,0.0004283152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001652788,"about_ca_system_score_gemma":0.00006895402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001890495,"about_ca_topic_score_gemma":0.0001367037,"domain_scores_codex":[0.9998705,0.00002522034,0.00001420289,0.00002106221,0.00002077788,0.00004823387],"domain_scores_gemma":[0.9999245,0.00001342759,0.00002265944,0.00001149674,0.000008579728,0.00001931625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003718246,0.00003763559,0.002817229,0.00004522305,0.000006515514,0.0001620283,0.00004163581,0.00004357914,0.9938466,0.00002469636,0.00003520004,0.002567877],"study_design_scores_gemma":[0.00009800713,0.003718156,0.1403664,0.00002373123,0.0001047616,0.007044643,0.0003365089,0.002138994,0.8424856,0.0002712583,0.003396572,0.00001534093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988387,0.0004546611,0.0003292038,0.00001948009,0.000002788377,0.000007046333,0.00008698126,0.0000267804,0.0002343914],"genre_scores_gemma":[0.9991897,0.0001247852,0.0001621461,0.00002885968,0.000004344596,0.00001407334,0.0001842156,0.00000581496,0.0002861286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001262185,"threshold_uncertainty_score":0.004222453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01899175564976743,"score_gpt":0.2450985272884921,"score_spread":0.2261067716387246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}