{"id":"W2510108885","doi":"10.1007/112_2016_6","title":"Hepatic Stellate Cells in Liver Fibrosis and siRNA-Based Therapy","year":2016,"lang":"en","type":"review","venue":"Reviews of physiology, biochemistry and pharmacology","topic":"Liver physiology and pathology","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of Manitoba","funders":"","keywords":"Hepatic stellate cell; Gene silencing; Cirrhosis; Small interfering RNA; Fibrosis; Cancer research; RNA interference; Medicine; Extracellular matrix; Genetic enhancement; Hepatic fibrosis; Pathology; Biology; Cell biology; RNA; Internal medicine; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004913457,0.0008926981,0.001505668,0.001796915,0.0002224036,0.000852977,0.0006832568,0.0008562135,0.002933719],"category_scores_gemma":[0.0003864517,0.0002676198,0.0005203622,0.001532612,0.0004441278,0.0008133546,0.0006493166,0.001465937,0.002029631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003214908,"about_ca_system_score_gemma":0.0007064877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005670922,"about_ca_topic_score_gemma":0.001248479,"domain_scores_codex":[0.9998533,0.00001722783,0.00002460445,0.00002148287,0.00006735286,0.00001613362],"domain_scores_gemma":[0.9998671,0.00005594833,0.00002438239,0.000005589295,0.00003249243,0.00001444015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001574539,0.0001146778,0.0001300099,0.01794246,0.000112534,0.000203491,0.00004642657,0.0003879359,0.01580315,0.003349484,0.02136069,0.9403916],"study_design_scores_gemma":[0.00005505996,0.000202482,0.0007629632,0.002043901,0.0002378585,0.0009622782,0.00003480565,0.0001636991,0.004604334,0.001894837,0.9890051,0.00003275356],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002214112,0.9979235,0.0004435792,0.0001646134,0.0002364962,0.000008628275,0.00002654499,0.00001716756,0.000958042],"genre_scores_gemma":[0.0009905249,0.9972444,0.0003897866,0.0001737076,0.0001530916,0.00001195903,0.00004952504,0.000002540878,0.0009843828],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002933719,"threshold_uncertainty_score":0.009814262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05018922067370545,"score_gpt":0.3620247486485456,"score_spread":0.3118355279748401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}