{"id":"W2510230378","doi":"10.1097/tp.0000000000001432","title":"Recent Advances in Mammalian Target of Rapamycin Inhibitor Use in Heart and Lung Transplantation","year":2016,"lang":"en","type":"review","venue":"Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta","funders":"","keywords":"Everolimus; Medicine; Lung transplantation; Sirolimus; Transplantation; Heart transplantation; Population; Adverse effect; Intensive care medicine; Calcineurin; PI3K/AKT/mTOR pathway; Clinical trial; Pharmacology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00055936,0.0004345278,0.001656812,0.0008283216,0.00002856516,0.00001730267,0.00007511666,0.0003578337,0.0000681182],"category_scores_gemma":[0.00002717356,0.000333535,0.0001979106,0.0005029798,0.00007849265,0.0005329947,0.000002876161,0.0003337502,0.000005578811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001066705,"about_ca_system_score_gemma":0.0001807173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004363644,"about_ca_topic_score_gemma":0.0004655289,"domain_scores_codex":[0.9971081,0.0004295922,0.001286997,0.0005225695,0.0003282357,0.0003244761],"domain_scores_gemma":[0.9986786,0.0006774173,0.0002797214,0.0001964404,0.0000573432,0.0001105094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001301395,0.0001570072,0.02696927,0.1173363,0.00006794919,0.0002807383,0.001561072,0.000007721672,0.0002400767,0.0001989504,0.00001039598,0.8518691],"study_design_scores_gemma":[0.01885342,0.000640506,0.1318546,0.2173886,0.004185409,0.001698678,0.0001426004,0.00003026893,0.002027023,0.0002561417,0.6211387,0.001784015],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003513101,0.9920393,0.001775627,0.0001142974,0.0002536246,0.001582648,0.0005725682,0.00003485452,0.0001139546],"genre_scores_gemma":[0.0007035882,0.9907075,0.007208489,0.00004444004,0.0000734711,0.0001061669,0.001044023,0.0000556802,0.00005662534],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8500851,"threshold_uncertainty_score":0.9999117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04337301034004402,"score_gpt":0.3687596111096559,"score_spread":0.3253866007696119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}