{"id":"W2510230378","doi":"10.1097/tp.0000000000001432","title":"Recent Advances in Mammalian Target of Rapamycin Inhibitor Use in Heart and Lung Transplantation","year":2016,"lang":"en","type":"review","venue":"Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta","funders":"","keywords":"Everolimus; Medicine; Lung transplantation; Sirolimus; Transplantation; Heart transplantation; Population; Adverse effect; Intensive care medicine; Calcineurin; PI3K/AKT/mTOR pathway; Clinical trial; Pharmacology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001021211,0.0004772937,0.0008966594,0.001556321,0.0001559826,0.0009474917,0.0004342495,0.0005670054,0.003234621],"category_scores_gemma":[0.001712277,0.0001721984,0.0007164239,0.001633196,0.0002244635,0.0009892456,0.0004567918,0.001238078,0.0009013828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004062018,"about_ca_system_score_gemma":0.0008313191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005084177,"about_ca_topic_score_gemma":0.001085972,"domain_scores_codex":[0.9996562,0.00007725406,0.0001093112,0.00005146868,0.00008078101,0.00002494918],"domain_scores_gemma":[0.9988093,0.0006688612,0.0002027688,0.00001949244,0.0002285305,0.0000711168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002419862,0.00006009494,0.0006855908,0.02259717,0.0001744368,0.0003063856,0.00006808514,0.0002521987,0.00136379,0.001097625,0.02855982,0.9445928],"study_design_scores_gemma":[0.0000626306,0.0005063414,0.004259924,0.009169728,0.0008942867,0.004865666,0.00009491452,0.0002167003,0.00106014,0.001427267,0.977401,0.00004128933],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003427136,0.997502,0.0001623815,0.0006051906,0.0005286314,0.000004360712,0.00002525109,0.000009508706,0.0008199614],"genre_scores_gemma":[0.001735105,0.9959238,0.000295429,0.0005486836,0.001179507,0.000006612889,0.00006452599,0.000003059813,0.0002433795],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003234621,"threshold_uncertainty_score":0.01082093,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04337301034004402,"score_gpt":0.3687596111096559,"score_spread":0.3253866007696119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}